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OpenTrials
Completed

NCT Number: NCT04974606

Effect of Coffeeberry on Mood, Motivation and Cognitive Performance

The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance.

Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.

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Key information

Conditions

Fatigue, Mental Alertness Behavior Behavioral Symptoms Cognitive Performance Fatigue Mental Fatigue Mood Motivation Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

17 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Exercise Psychology Laboratory University of Georgia

Athens, Georgia, 30601, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Are older than 17 and under 50 years of age
  • Self-report of good health

Exclusion criteria

  • Using any prescription medication including birth control
  • Report hypersensitivity to caffeine
  • Have visual impairment that cannot be corrected with glasses or contact lenses
  • Report any food allergies
  • Self-reported excessive leisure time physical activity (> 7 strenuous bouts per week)
  • the presence of current gastrointestinal, sleep, or psychiatric disorder,
  • Report pregnancy/lactation, illegal drug use, smoker
  • failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks.
  • Participation in another clinical trial within past 30 days

Treatment and study plan

Cherry-flavored still beverage

Dietary Supplement

10 oz bottle

Placebo cherry-flavored still beverage

Other

10 oz bottle

Primary outcomes

  1. Cognition score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Higher test scores are better.

    Objective Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) for word and picture presentation and recall, serial 3 and 7 subtraction, Rapid Visual Information Processing (RVIP).

  2. Fatigue score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Lower fatigue score is better.

    Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)

  3. Alertness score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Higher alertness score is better.

    Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)

  4. Calmness score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Higher calmness score is better.

    Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)

  5. Contentedness score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Higher contentedness score is better.

    Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)

  6. Motivation score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Higher motivation score is better.

    Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)

  7. Energy score

    Time frame: Change from baseline to 60 and 120 min post-consumption. Stronger feelings of mental and physical energy are better.

    Subjective mental and physical state energy and fatigues scales (EFS-State Scale). Composite scores range from 0 to 300 mm, from feelings of no energy to strongest feelings of energy during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)

Sponsors and collaborators

Lead sponsor

PepsiCo Global R&D

Industry

Registry information

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Jul 23, 2021
Registry last updated
Jul 23, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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