Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)

This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs.

Hypothesis:

Normal saline or cefazolin irrigation decreases the incidence of SSIs.

Completed

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Key information

Conditions

Surgical Site Infections Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Surgical Wound Infection Wound Infection

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Shariati Hospital

Bandar Abbas, Hormozgan, 79176, Iran

About this study

All pregnant women who underwent cesarean after 6 hours passed their rupture of membrane and attended to Shariati Hospital of Bandarabbass were eligible for our study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

pregnant women
6 hours passed their rupture of membrane
needed to undergo cesarean

Exclusion criteria

allergy to penicillin
allergy to cefazolin
history of immunosuppressive drug use
gestational diabetes mellitus
preeclampsia

Treatment and study plan

Cefazolin irrigation

Other

after the surgery and before closing up the patients, 2 grams of cefazolin in 5 cc of distilled water was used to irrigate the patients

Other names: cephazolin, cefazoline, Ancef, Cefacidal, Cefamezin, Cefrina, Elzogram, Faxilen, Gramaxin, Kefazol, Kefol, Kefzolan, Kezolin, Novaporin, Reflin, Zinol, Zolicef

Normal Saline Irrigation

Other

after the surgery and before closing up the patients, 150 cc of normal saline was used to irrigate the patients and in the last group

Other names: sodium chloride, saline solution

Primary outcomes

SSI

Time frame: one week after discharge

Sponsors and collaborators

Lead sponsor

Hormozgan University of Medical Sciences

Other

Registry information

Official study title

Comparison of the Effect of Cefazolin and Normal Saline Irrigation With no Irrigation on the Incidence of Surgical Site Infections

Important dates

Study start: 2010
Primary completion: 2011
Study completion: 2012
First posted: Mar 29, 2012
Registry last updated: Oct 15, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed