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Completed

NCT Number: NCT07263126

Effect of Bicycle Ergometer Training on Fat Tissue Amount and Metabolism

The aim of this study is to investigate the effect of endurance training performed with a bicycle ergometer at different ambient temperatures on the amount of fat tissue and fat tissue metabolism in overweight and obese women.

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Key information

Conditions

Endurance Training Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Şule Şimşek

Denizli, Sarayköy, 09200, Turkey (Türkiye)

About this study

This study will examine the effects of 12 weeks of endurance training on a bicycle ergometer at thermoneutral and slightly cold ambient temperatures on body composition, subcutaneous and visceral fat tissue thickness, and levels of irisin, leptin, adiponectin, apelin, IL-6 and FGF-21 in the blood of overweight and obese women.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Being female,

  • Being between 20-40 years old,
  • Having a BMI between 25 and 34.9,
  • Having a waist circumference greater than 80 cm,
  • Not having participated in any exercise program in the last 3 months ,
  • Not having experienced a change of more than 10% in body weight in the last 6 months.

Exclusion criteria

  • On a weight loss diet,
  • Having cancer, unstable heart disease, cerebrovascular disease, metabolic disease, diabetes, hypertension, psychiatric disorders, or other conditions or neurological disorders,
  • Having a musculoskeletal disorder or any disease/injury that may affect participation in exercise training,
  • Participating in regular physical activity (at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity or an equivalent combination of both during the week),
  • Being pregnant or breastfeeding,
  • Having undergone surgery for the treatment of obesity,
  • Receiving pharmacological treatment for obesity. Participants who did not attend more than 20% of the endurance training program will be excluded from the study.

Treatment and study plan

endurance training with bicycle ergometer in termoneutral ambient temperature

Other

trained with bicycle ergometer three times a week for three months.

endurance training with bicycle ergometer in lightly cold ambient temperature

Other

trained with bicycle ergometer three times a week for three months.

Primary outcomes

  1. rate of BMI

    Time frame: baseline/ through study completion, an average 3 months

    assesed with height and body weight

  2. analysis of biyoelectric impedans Bioelectrical impedance analysis

    Time frame: baseline/ through study completion, an average 3 months

    assesed with with a Tanita BC 418 brand device.

  3. Ratio of waist-hip Waist hip ratio

    Time frame: baseline/ through study completion, an average 3 months

    Waist and hip circumference will be measured with a tape measure.

  4. rate of subcutaneous and visceral adipose tissue thickness

    Time frame: baseline/ through study completion, an average 3 months

    assesed with Ultrasonography

  5. concentration of serum irisin, adiponectin, apelin and İL-6

    Time frame: baseline/ through study completion, an average 3 months

    assesed with blood analysis

Sponsors and collaborators

Lead sponsor

Pamukkale University

Other

Registry information

Official study title

Effect of Bicycle Ergometer Training in Thermoneutral and Lightly Cold Ambient Temperatures on Fat Tissue Amount and Metabolism in Overweight and Obese Women

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Dec 4, 2025
Registry last updated
Jul 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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