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OpenTrials
Completed

NCT Number: NCT01745016

Effect of Beta-Alanine on Heart Rate Response

Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.

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Key information

Conditions

Exercise Behavior Fatigue Motor Activity Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UNC Exercise and Sport Science

Chapel Hill, North Carolina, 27599, United States

About this study

An equal number of men and women will be recruited [Men, n=20 (10 placebo [PL]; 10 beta-alanine (Active)]; [Women,n=20 (10 PL; 10 Active)]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between the ages of 18-35 years old
  • Be recreationally active (defined as accumulating 1-5 hours of moderate intensity

Exclusion criteria

  • Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire
  • Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months

Treatment and study plan

Placebo

Dietary Supplement

Beta-alanine

Dietary Supplement

Primary outcomes

  1. Physical working capacity at heart rate threshold

    Time frame: 0 to 4 weeks

Sponsors and collaborators

Lead sponsor

University of North Carolina, Chapel Hill

Other

Registry information

Official study title

The Effect of 28 Days of Beta-alanine Supplementation on the Physical Working Capacity at Heart Rate Threshold (PWCHRT)

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Dec 7, 2012
Registry last updated
Apr 30, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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