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Completed

NCT Number: NCT05499819

Effect of Beans Compared to Beef on Satiety in Older Adults

This human clinical trial is using a randomized crossover design to examine the effect of two varieties of beans compared to beef on satiety and food intake in older adults.

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Key information

Conditions

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Human Nutraceutical Research Unit

Guelph, Ontario, N1G 2W1, Canada

About this study

This human clinical trial is using a randomized crossover design that includes 3 study visits separated by washout periods of at least 1 week. Each study visit will last approximately 4 hours and will occur at the Human Nutraceutical Research Unit (HNRU) at the University of Guelph. Study visits will occur in the morning and begin with measurement of fasting body weight. Participants will then complete a baseline satiety questionnaire before they consume a breakfast test meal (that includes either red kidney beans, black beans or extra-lean ground beef). After the breakfast meal, participants will complete a palatability questionnaire. They will also complete more satiety questionnaires at 15, 30, 45, 60, 120, 150 and 180 minutes. After 180 minutes, participants will be consume an ad libitum pizza lunch meal until they are comfortably full. Participants will then be sent home with a food scale and instructions to record everything they eat and drink for the remainder of the day.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy males and females
  • ≥60 years old
  • BMI between 18.5-30 kg/m2

Exclusion criteria

  • Medication use that is not at a stable dose (at least 3 months)
  • Natural health product use that is not at a stable dose (at least 3 months)
  • Antibiotic use in the past 3 months
  • Overnight shift work
  • Alcohol consumption >14 drinks/week or >4 drinks/sitting
  • Anaphylactic food allergy
  • Pulse (beans, lentils, chickpeas, dried peas) consumption >4 servings per week
  • Recent or intended significant weight loss or weight gain (>4 kg in previous 3 months)
  • Breakfast skipping ≥4 days per week
  • Vegan diet
  • Dislike or unable to consume beans, ground beef, shredded cheddar cheese, white tortilla wraps or frozen cheese pizza
  • Three Factor Eating Questionnaire scale scores >11 for Cognitive Restraint, >9 for Disinhibition, and >8 for Hunger
  • Diagnosed hypertension (blood pressure >140/90mmHg) that is not managed
  • Diagnosed digestive-related condition (i.e. Celiac Disease, constipation, gastritis, gastroesophageal reflux disease, gluten intolerance, hemorrhoids, inflammatory bowel disease (Crohn's, Ulcerative Colitis), irritable bowel syndrome, lactose intolerance)
  • Diagnosed cognitive-related condition (i.e. Alzheimer's Disease, amnesia, dementia, generalized anxiety disorder, major depressive disorder, Parkinson's Disease, schizophrenia, traumatic brain injury)
  • Medical condition that does not have stable management for at least 3 months
  • Medical or surgical event requiring hospitalization in the past 3 months
  • Tobacco use
  • Cannabis use
  • Vape use

Treatment and study plan

Canned black beans, drained and rinsed

Other

Canned black beans, drained and rinsed and consumed in a tortilla wrap

Canned red kidney beans, drained and rinsed

Other

Canned red kidney beans, drained and rinsed, drained and rinsed and consumed in a tortilla wrap

Extra-lean ground beef

Other

Extra-lean ground beef, pan-fried and consumed in a tortilla wrap

Primary outcomes

  1. Subjective appetite sensations

    Time frame: Area under the 180 minute curve

    Fullness, satisfaction, hunger, desire to eat, prospective food consumption (measured by a visual analogue scale in mm)

Secondary outcomes

  1. Food intake at an ad libitum pizza meal

    Time frame: 180 minutes after consumption of study treatment (in a breakfast meal)

    Food intake will be measured in grams at an ad libitum cheese pizza lunch meal

  2. 24-hour energy intake

    Time frame: 24 hours

    Energy intake measured as kcal for 24 hours after consumption of study treatment (in a breakfast meal) using a weighed food record

Sponsors and collaborators

Lead sponsor

University of Guelph

Other

Collaborators

  • Ontario Bean Growers

Registry information

Official study title

The Effect of Beans Compared to Beef on Satiety and Food Intake in Older Adults

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Aug 12, 2022
Registry last updated
May 10, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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