Abouqir General Hospital
Alexandria, 21527, Egypt
NCT Number: NCT03791710
the study evaluates the role of autologous fat grafting and the usage of nanofat in the treatment of the acute burn injuries in different genders and its influences on the healing time and hospital stay, pain control, the need and take of a split thickness skin graft and its size, and the end resulting early scarring, in comparison with control group that were treated with traditional methods, so as to find out new method of treating burn injuries and decreasing its morbidity.
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Notify Me13 year–60 year
All sexes
Interventional
Phase 3
Alexandria, 21527, Egypt
as the patient is admitted, full evaluation locally ( as regard the wound itself and the areas of fat harvesting) and generally (assessment of the general condition) is done, fluid resuscitation is started as the unit protocol hand in hand with the analgesia and other medications prescribed according to the unit protocol.
the patient's general condition is optimized for surgery of the fat extraction and grafting which typically should be within the first 6 days of admission.
then under anesthesia (any possible type from local and regional up to general anesthesia) liposuction procedure is performed, then fat is processed then grafted at the wound site with other portion prepared as nanofat for topical use and wound coverage, then sterile dressing is applied.
typically follow up is held daily with the dressing change day after another with the use of the nanofat only and sterile dressing
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
regular liposuction procedure at which sufficient amount of fat is extracted from the patient and then the fat is processed then grafted underneath the burn wound
Other names: liposuction and lipofilling
serial dressing with topical agents e.g Silver Sulphadiazine
Other names: dressing
depridment and split thickness skin grafting
Other names: skin grafting
Time frame: one to three weeks
the effect of the fat grafting on the wound healing time
Time frame: immediate post-operative and up to three weeks
effect of the fat grafting on the pain sensation in the burn wound, assessment through a numerical scale starting at "0" indicating no pain at all to "10" the most intense severe pain. the range between "1" and "3" describes mild pain, between "4" and "6" describes moderate pain, and lastly from "7" to "10" severe pain.
Ahmed Mohamed Abouzaid
Other
Effect of Autologous Fat Grafting and Nanofat Usage on Burn Wound Healing and Early Scarring
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