UCSD
La Jolla, California, 92093, United States
Location status: Recruiting
Recruiting
NCT Number: NCT04748809
Effect of Anti-inflammatory Diet in Rheumatoid Arthritis
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits.
Exclusion criteria
- Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study.
- Food allergies
- Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretation of the results
Treatment and study plan
Diet 1
OtherDietary intervention
Other names: anti-inflammatory diet 1
Diet 2
OtherDietary intervention
Other names: anti-inflammatory diet 2
Primary outcomes
-
Decrease of more than 5 points in Clinical Disease Activity Index
Time frame: 3 months
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
University of California, San Diego
Other
Registry information
Official study title
An Evaluator-blinded Randomized Controlled Trial Study of the Effect of Anti-inflammatory Diet in Subjects With Rheumatoid Arthritis.
Important dates
- Study start
- 2020
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Feb 10, 2021
- Registry last updated
- Jan 9, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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