Effect of an Iridoid Enriched Beverage on Skin Autofluorescence

Inclusion criteria

• Males and females age 25 to 60 years.
• Overweight or obese, defined as BMI 23.0 to 39.9 kg/m2.
• Impaired fasting glucose, defined as fasting blood glucose 100 to 125 mg/dl.
• Prehypertension or Grade 1 hypertension, defined as systolic blood pressure 120-159 mm Hg AND diastolic BP 80-99 mm Hg.
• Ability of the participant (in the investigator's opinion) to comprehend the full nature and purpose of the study including possible risks and side effects.
• Consent to the study and willing to comply with study procedures.

Exclusion criteria

• Prescription medication use for hypertension, high cholesterol, diabetes, heart disease, cancer, liver disease, or AIDS/HIV 2.
• Intake of foods and/or dietary supplements that may confound study outcomes including any use of a noni-based dietary supplement in the last month.
• Regular use (> 3 times per week over the past month) of any dietary supplement that contains "super fruits" or high antioxidant concentrations.
• Regular use (> 3 times per week over the past month) of any dietary supplement intended to alter or regulate blood glucose levels.
• Any medical conditions or diseases that may affect subject safety or confound study results (in the opinion of the investigator).
• Pregnant or lactating female.
• History of alcohol, drug, or medication abuse.
• Current heavy smokers (1 or more packs/day).
• Allergies to any ingredient in the investigational products.
• Participation in another study with any investigational product.