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NCT Number: NCT06935448

Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy

This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program.

This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.

Recruiting

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Key information

Conditions

Pancreatectomy Enhanced Recovery After Surgery Pancreatic Cancer Resectable

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Thessaly

Larissa, Greece

Location status: Recruiting

About this study

This prospective observational study is conducted by the same surgical team at two high-volume pancreatic cancer referral centers in Greece.

Patients undergoing elective pancreatic surgery are prospectively enrolled and managed according to a standardized ERAS protocol (ERAS group).

A control group, which received standard perioperative care before the implementation of ERAS, was retrospectively selected and matched based on demographic and clinical parameters.

The primary study endpoint is the length of hospital stay (LOS), while secondary endpoints include 30-day mortality and morbidity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients
  • diagnosis of pancreatic cancer
  • elective open pancreatic surgery

Exclusion criteria

  • age <18 years
  • emergency pancreatic surgery
  • other surgical procedures
  • missing data
  • lost to follow-up

Treatment and study plan

Enhanced recovery after surgery

Other

ERAS group follows the enhanced recovery after surgery program which involves 20 elements

Primary outcomes

  1. impact on length of stay

    Time frame: within 30 days of surgery

    total number of days spent in the hospital including any readmission

Secondary outcomes

  1. impact on overall morbidity

    Time frame: within 30 days from surgery

    number of any perioperative adverse events

Study contacts

Contact information is provided by the study sponsor or research team.

ATHINA SAMARA, MD MSc PhD(c)

CONTACT

[email protected]

DESPOINA LIOTIRI, MD MSc PhD(c)

CONTACT

[email protected]

00302410996000

Sponsors and collaborators

Lead sponsor

University of Thessaly

Other

Registry information

Official study title

Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy; Experience From Two Referral Centers in Central Greece.

Important dates

Study start
2019
Primary completion
2025
Study completion
2025
First posted
Apr 20, 2025
Registry last updated
Apr 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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