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OpenTrials
Completed

NCT Number: NCT00659698

Effect of an Artificial Pancreas in Patients Undergoing Hepatic Resection

This study evaluated that strict control of perioperative blood glucose following hepatic resection by using an artificial pancreas would improve postoperative surgical site infection.

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Key information

Conditions

Liver Diseases Digestive System Diseases Infections

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Kochi Medical School

Nankoku, Kochi, 783-8505, Japan

About this study

This study recruited 70 patients undergoing elective hepatic resection for liver diseases. Perioperative blood glucose concentration was continuously monitored using an artificial pancreas system. We prospectively divided patients into two groups: one for whom glucose levels were controlled using a manual injection of insulin according to the commonly used sliding scale and another that received programmed infusions of insulin determined by the control algorithm of the artificial pancreas.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • This study recruited 70 patients undergoing elective hepatic resection for liver diseases. Perioperative blood glucose concentration was continuously monitored using an artificial pancreas system.

Exclusion criteria

  • weight loss greater than 10% during the previous 6 months, signs of distant metastasis, and respiratory, renal, or heart disease

Treatment and study plan

the closed-loop STG-22 system (Nikkiso Inc, Tokyo, Japan)

Device

artificial pancreas

Other names: an artificial pancreas system (Nikkiso Inc, Tokyo, Japan)

Primary outcomes

  1. the incidence of surgical site infection

    Time frame: 30th postoperative day

Secondary outcomes

  1. the incidence of hypoglycemia and cost during the hospitalization

    Time frame: during the hospitalization

Sponsors and collaborators

Lead sponsor

Kochi University

Other

Registry information

Official study title

Prevention for Surgical Site Infection After Hepatic Resection

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Apr 16, 2008
Registry last updated
Apr 16, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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