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Completed

NCT Number: NCT01827696

Effect of American Ginseng on Exercise-induced Muscle Soreness

Healthy participants will ingest American ginseng daily or a placebo for four weeks prior to engaging in a unaccustomed exercise bout designed to induce mild-moderate muscle soreness. Muscle soreness will be assessed via decrements in muscle strength and with a self-rating of perceived soreness before and several times after the exercise.

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Key information

Conditions

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

University of Western Ontario

London, Ontario, N6A 3K7, Canada

About this study

Healthy men and women will consume either 2000 mg of American ginseng daily (four 500 mg pills will be taken at four different times during the day always with food/meals) or a placebo (4 cellulose) for four weeks prior to engaging in a 40 minute downhill treadmill jog (12% decline) at a speed of 7 miles per hour. Participants will consume one pill with breakfast, one pill with lunch, one pill with dinner and another pill with a snack either between meals or prior to bedtime. The exercise will be consist of five, eight minute bouts of jogging with two minutes of rest/recovery in between. The degree of muscle soreness will be assessed using a Biodex strength testing machine (isometric and concentric isokinetic torque), and a self-rating of perceived soreness on a scale from zero to ten. All of the above measures will be taken before and several times after the downhill jogging protocol.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy men or women, (women must weigh between 55-65 kg., while men must weigh between 75-85kg).
  • Participants must not have engaged in any endurance run training in the past 9 months.

Exclusion criteria

  • Injured
  • Regular runners
  • Pregnant (or with any chance they may become pregnant)
  • Breast-feeding
  • Diabetics or those taking medication for diabetes
  • Insomniacs
  • Schizophrenics
  • Hyper- or hypotension
  • Cancer
  • Irregular heartbeats
  • Heart disease
  • Females with endometriosis or uterine fibroids
  • Those who have surgery scheduled during the study or within the two weeks following the completion of the study
  • Those taking warfarin or medication for depression.

Treatment and study plan

Ginseng

Dietary Supplement

Effect of four weeks of daily Ginseng intake (2gm/day) on muscle soreness following downhill running exercise

Primary outcomes

  1. muscle strength

    Time frame: 1 month

    ginseng & muscle strength

Sponsors and collaborators

Lead sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Other

Registry information

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Apr 9, 2013
Registry last updated
Mar 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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