Skip to main content
OpenTrials
Completed

NCT Number: NCT05987436

Effect of Aerobic Exercise in Patients With Essential Hypertension

The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Aerobic Exercise Cardiovascular Diseases Essential Hypertension Hypertension Vascular Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Selcuk University Faculty of Medicine

Konya, Turkey (Türkiye)

About this study

Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Over 18 years of age,
  • Absence of concomitant other metabolic and cardiovascular diseases.

Exclusion criteria

  • Having suffered an event of ischaemic heart disease (<6 months),
  • Secondary hypertension,
  • Hypertrophic obstructive cardiomyopathy,
  • Congestive heart failure,
  • Uncontrolled cardiac arrhythmia,
  • Thyroid dysfunction,
  • Diabetes mellitus,
  • Symptomatic peripheral arterial occlusive disease,
  • Aortic insufficiency or stenosis,
  • Pulmonary or heart disease with dyspnoea at small or moderate effort,
  • An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis,
  • Using of antidepressant or anxiolytic drugs,
  • Pregnancy,
  • Cognitive disfunction.

Treatment and study plan

supervised aerobic exercise

Other

Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Primary outcomes

  1. Body weight

    Time frame: was measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician.

    kilograms

  2. Blood samples

    Time frame: Twelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6.

    Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides

  3. The functional capacity

    Time frame: 6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed.

    The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity.

  4. Quality of Life

    Time frame: SF36 was assessed in face-to-face interviews before and immediately after the treatment was completed.

    Quality of life was assessed with Short Form-36 (SF-36).

  5. Depression level

    Time frame: BDI was assessed in face-to-face interviews before and immediately after the treatment was completed.

    Depression level was assessed Beck Depression Inventory (BDI).

Sponsors and collaborators

Lead sponsor

TC Erciyes University

Other

Registry information

Official study title

Effects of Supervised Versus Unsupervised Aerobic Exercise Training on Weight Loss, Functional Capacity, Quality of Life and Depression Level in Patients With Essential Hypertension

Important dates

Study start
2017
Primary completion
2019
Study completion
2019
First posted
Aug 14, 2023
Registry last updated
Aug 14, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.