Effect of Adding Sufentanil to Epidural Ropivacaine on Perioperative Metabolic and Stress Responses in Combined General/Epidural Anaesthesia for Geriatric Radical Retropubic Prostatectomy

The purpose of this study is to compare metabolic and stress responses in combined general/epidural anesthesia in geriatric cancer patients.

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Key information

Conditions

Prostatic Cancer Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Site Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Severance Hospital

Seoul, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

elective RRP for prostatic cancer scheduled in the morning (9-11 a.m.)
patients aged more than 65 years
ASA physical status I or II
absence of contraindications to epidural approach
absence of a history of chronic pain or opioid medication

Exclusion criteria

contraindication to epidural catheterization

Treatment and study plan

epidural infusion of saline, ropivecaine, or ropivacaine and sufentanil

Drug

Primary outcomes

plasma glucose, insulin, cortisol, epinephrine, norepinephrine, prolactin

Time frame: from preoperative baseline to postoperative 24 hours

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Mar 15, 2010
Registry last updated: Nov 11, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed