Skip to main content
OpenTrials
Completed

NCT Number: NCT05325307

Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety Level

This randomized controlled study evaluates the effect of acupressure application on the anxiety level patients undergoing cystectomy surgery. The hypothesis of this study is that acupressure reduces anxiety levels and stabilizes hemodynamic parameters.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Anxiety Anxiety Disorders Hemodynamic Instability Mental Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Turkey, Mersin University,

Mersin, Turkey/Mersin,Yenişehir, 33343, Turkey (Türkiye)

About this study

In the study, 60 patients will randomly assigned to acupressure and placebo acupressure groups. To the acupressure group (n = 30), an average of 15 minutes will be applied to the HT7 (heart), LI4 (liver) and EX-NH3 (the point between the two eyes). In the placebo acupressure group (n = 30), the points 1.5 cm away from the HT7, LI4, and EX-NH3 points will be applied for an average of 15 minutes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Agreeing to participate in the research (signing the Informed Consent Form),
  • Conscious and cooperative
  • Speaks and understands Turkish,
  • 18-65 years old,
  • Before surgery,
  • Stable general condition,
  • No sensitivity in the area where acupressure/placebo acupressure will be applied,
  • 15 July 2022 - 15 July 2023 hospitalized in the urology clinic,
  • No active COVID-19 infection,
  • Patients without any psychiatric diagnosis will be included.

Exclusion criteria

  • Those who do not agree to participate in the research (who do not sign the Informed Consent Form)
  • Conscious and uncooperative,
  • Not speaking or understanding Turkish,
  • Not between the ages of 18-65,
  • No surgical intervention planned,
  • The planned emergency surgical intervention,
  • Unstable general condition,
  • Sensitivity in the area where acupressure/placebo acupressure will be applied,
  • Active COVID-19 infection,
  • 15 July 2022 - 15 July 2023 who did not stay in the urology clinic,
  • Patients with current psychiatric diagnosis will not be included in the study.

Treatment and study plan

Acupressure

Other

The experimental group will start with HT7 points and continue LI4 and EX-NH3 points. The application will be carried out by determining the priority order of the points with the draw. Attention will be paid to the intensity and duration of the pressure deemed appropriate. Since the individuals' responses will differ, the stiffness and pressure will be adjusted according to the individual's sensitivity not to cause tissue damage. Before starting the application, around the area to be pressed for 20-30 seconds will be gently rubbed with palm. With the gentle rubbing of the surrounding tissue, the tension and tissue sensitivity in warming, relaxing and preparatory will be reduced, and the tissue will be relieved. After, the point determined will be pressed manually for 2 minutes.

Placebo acupressure

Other

In the placebo acupressure group , the points 1.5 cm away from the HT7, LI4, and EX-NH3 points will be applied for an average of 15 minutes. Less pressure will be applied.

Primary outcomes

  1. Anxiety evaluated using the State Anxiety Scale

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    Scores ranging from 20 to 80 points are obtained in the scale. In the total score obtained from the scale in scoring the scale, 0-19 points indicate the absence of anxiety, 20-39 points indicate mild anxiety, 40-59 points indicate moderate anxiety, and 60-79 points indicate severe anxiety level. Higher state anxiety scores indicate that anxiety level is also high

Secondary outcomes

  1. Systolic blood pressure

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    Systolic blood pressure (SBP), mmHg

  2. Diastolic blood pressure

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    Diastolic blood pressure (DBP), mmHg

  3. Heart rate

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    Beats per minute

  4. Respiratory rate

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    Lung breathing

  5. Peripheral oxygen saturation

    Time frame: Change from before implementation and immediately after, 20th minute after acupressure

    %, percentage of oxygenated hemoglobin in peripheral arterial blood

Sponsors and collaborators

Lead sponsor

Mersin University

Other

Registry information

Official study title

Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety Level: Three Blind Randomized Controlled Studies

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Apr 13, 2022
Registry last updated
Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.