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OpenTrials
Completed

NCT Number: NCT06689644

Effect of a Plant Based Nootropic on Perceptual Decision Making.

Nootropics are a group of medicinal substances purported to improve important cognitive functions such as learning, focus and memory. Many of these substances have demonstrated beneficial effects on cognitive performance and overall health. However, a thorough understanding of how these substances and their synergistic effects in the form of a supplement may benefit fundamental brain processes is currently lacking. In the current study, we will investigate the effects of a plant-based, nootropic supplement (https://uk.mindlabpro.com/) on perceptual decision-making (i.e. the ability to make rapid decisions based on sensory stimuli) in healthy adult participants.

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Key information

Conditions

Cognitive Enhancement

Age range

20 year–59 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Biological sciences

Leeds, United Kingdom

About this study

Participants will perform a computerised cognitive task assessing their perceptual decision-making pre- and post- 60 days of continuous supplementation with either a plant-based nootropic supplement (Mind Lab pro) or placebo. During testing, electroencephalography (EEG) signals will be captured simultaneously.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eligibility screening of participants was guided by the following inclusion criteria: (i) be between 20-59 years old, (ii) be right-handed and (iii) be able to cease taking other dietary supplements for two months.

Exclusion criteria

  • Exclusion criteria included: (i) currently consuming a nootropic supplement, (ii) any known musculoskeletal, or neurological medical conditions or cognitive impairments (iii) have a known diagnosis of epilepsy/history of seizures and (iv) have a known hearing or visual condition that affects daily life function.

Treatment and study plan

Nootropics (ginkgo biloba, nicergoline, piracetam, or others)

Dietary Supplement

Commercially available product: Mind lab pro

Placebo

Dietary Supplement

A cellulose commonly used as a bulking agent in supplement products

Perceptual decision-making performance

Behavioral

A computerised cognitive task involving rapid visual categorisation of images

Electroencephalography

Device

Brain signals are recorded from a 64 channel EEG system during the cognitive task

Primary outcomes

  1. Perceptual decision-making performance

    Time frame: Pre- and post- 60 days of supplementation

    Choice accuracy and reaction times

Secondary outcomes

  1. Brain network interdependencies

    Time frame: Pre- and post- 60 days of supplementation

    Patterns extracted from brain signals using electroencephalography

Sponsors and collaborators

Lead sponsor

University of Leeds

Other

Registry information

Official study title

Effect of a Plant-based Nootropic Supplement on Perceptual Decision-making and Brain Network Interdependencies: a Randomised, Double-blinded and Placebo-controlled Study.

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Nov 14, 2024
Registry last updated
Nov 14, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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