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Completed

NCT Number: NCT06372262

Effect of 2000-meter Rowing Test on Parameters of Intestinal Integrity in Elite Rowers During Competitive Phase

The study aimed to check the 2000m ergometer test on markers of gut permeability in the competitive phase of rowers. 18 members of the Polish rowing team took part in the study.

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Key information

Conditions

Endothelial Dysfunction

Age range

18 year–23 year

Sex eligibility

Male

Study type

Observational

Primary location

Poznan University of Physical Education

Poznan, Poland

About this study

The phenomenon of epithelial wall leakage has been the subject of investigations within athletic domains such as running and cycling. Nevertheless, there exists an insufficiency of understanding regarding gut permeability in alternative disciplines, such as rowing, particularly following the completion of a standard competitive distance of 2000 meters. Hence, the principal objective of our study was to assess gut permeability after completing a 2000-meter rowing test. The study was performed at the beginning of a competitive training phase. Eighteen elite Polish Rowing Team rowers participated in the study after applying the inclusion/exclusion criteria. The participants performed a 2000-meter ergometer test. Blood samples were taken before the test, after exercise, and after 1-hour of restitution. Parameters, such as I-FABP, LPS, LBP, and zonulin, were determined using appropriate biochemical tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • minimum five years of training,
  • five training sessions per week minimum,
  • total training time minimum of 240 minutes,
  • membership in the Polish Rowing Team,
  • finishing the 2000-meter ergometer test.

Exclusion criteria

  • antibiotic therapy within the last three months,
  • probiotics and prebiotics within the last three months,
  • dietary regime,
  • gastrointestinal diseases.

Treatment and study plan

ergometer test

Other

2000meter rowing ergometer test

Primary outcomes

  1. I-FABP (intestinal fatty acid binding protein)to measure epithelial wall injury

    Time frame: Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

    I-FABP concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays

  2. zonulin to measure tight junction leakage

    Time frame: Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

    zonulin concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays

  3. LBP (lipopolysaccharide binding protein) to measure endotoxin

    Time frame: Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

    LBP concentration measured in blood [ug/ml] using commercially available enzyme-linked immunosorbent assays

  4. LPS (lipopolysaccharide) to measure endotoxin

    Time frame: Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period

    LPS concentration measured in blood [EU/Ll] using commercially available enzyme-linked immunosorbent assays

  5. Lactic acid to measure fatigue after the race

    Time frame: Blood samples was taken from earlobe at two-time points: before each stress test (after overnight fasting), one minute after the end of the test.

    Lactate concentration measured in capillary blood from earlobe [mmol/L] using a commercially available kit (Diaglobal, Berlin, Germany)

Secondary outcomes

  1. energy

    Time frame: day before test

    energy [kcal ]of food intake measured by 24h dietary recall

  2. fiber intake

    Time frame: day before test

    fiber [g] intake day before the test measured by 24h dietary recall

  3. protein

    Time frame: day before test

    protein [g] intake day before the test measured by 24h dietary recall

  4. carbohydrate

    Time frame: day before test

    carbohydrate [g] intake day before the test measured by 24h dietary recall

  5. body mass

    Time frame: in the morning before the test

    Body mass [kg] measured by electronic scale to the nearest 0,05 kg (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

  6. Body composition - water

    Time frame: in the morning before the test

    % of body water measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

  7. Body composition - fat

    Time frame: in the morning before the test

    % of body fat measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

  8. Lean body mass

    Time frame: in the morning before the test

    Lean body mass [kg] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan).

Sponsors and collaborators

Lead sponsor

Poznan University of Physical Education

Other

Registry information

Acronym: Rowers

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Apr 17, 2024
Registry last updated
Apr 17, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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