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Completed

NCT Number: NCT07002151

Educational Kinesiology Program's Effect on Cognition, Manual Dexterity and Bimanual Coordination in MS Patients

the purpose of this study was to evaluate the usefulness of educational kinesiology program to improve cognitive impairement, manual dexterity and bimanual coordination in patients with relapsing remitting multiple sclerosis. the study evaluated some domain of cognition as (attention & concentration, figural memory, reaction behavior and logical reasoning) manual dexterity and bimanual coordination were also evaluated of individuals with multiple sclerosis who went through the traditional as compared to others who used educational kinesiology training as part of their therapy.

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Key information

About this study

Multiple sclerosis (MS) is a chronic non-curative immune inflammatory demyelinating disease mainly affects the Central Nervous System. Cognitive deficits are common in MS and affect patients at all stages of the disease-including the early stage. There was a negative correlation between the employment of MS patients and their cognitive impairment assessed by information processing speed, memory, and executive function. Currently, the recommended treatments for cognitive dysfunction and depression in people with MS are cognitive retraining and cognitive behavioural therapy, respectively. Both of these approaches are time-consuming and are often unavailable away from major treatment centres. The common clinical signs of the disease include motor and sensory deficits, cerebellar symptoms, fatigue, and/or vision problems, which can impact manipulative dexterity in 76% of the population with MS. Often, patients also present bilateral impairments.Educational kinesiology program is the original 26 movements. The movements which are naturally done during the first years of life when learning coordinated the eyes, ears, hands and whole body are recalled by these activities. The principle behind Educational kinesiology program is that moving with intention leads to optimal learning. Educational kinesiology program has a beneficial effect on cognitive function and combines movement of the feet, hands in the optimization of left and right brain functions so as to improve cognitive function that were damaged or decrease.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female aged from 18-50 years.
  • Patients with relapsing remitting MS (RRMS).
  • EDSS scores for (RRMS) is ranging from 2.5 to 5.5 with a pyramid function score less than 2.
  • Gave their oral and written consent to participate in the training.
  • Adequate vision and hearing for completion of the study protocol, as indicated by the ability to follow written and oral instructions during screening.
  • Stable medical condition.

Exclusion criteria

  • Patients with communication problems.
  • Patients with a history of previous neurologic diseases or disorders.
  • Patients with other types of MS.
  • In co-operative patients.
  • Unhealed fracture, contracture, pressure sores that might interfere with training.
  • Untreated psychiatric disorders or ongoing drug abuse.

Treatment and study plan

educational kinesiology training program intervention for study group

Other

The Educational kinesiology program were included : (Cross crawl) Sit or stand and with the right-hand elbow touch the left knee and vice versa. (The owl) Bring one hand up to the opposite shoulder and hold a pinch around the trapezius muscle between the neck and shoulder. the thumb should be on one side of the muscle and the other fingers clasping around the other side. Turn the head to the same side as thehand is gripping and take a deep breath. Slowly exhale as bringing the head gently around to the other side. Repeat this movement one more time. (The arm activation) Hold one arm next to the ear. Exhale gently while activating the muscles by pushing the arm against the other hand in four directions (front, back, in and away). (The Energizer) Place the head on the desk in front exhale and inhale while coming up and try to hyperextend the neck carefully. (cook's hook-up) put the left ankle over your right knee. Next, hook the right hand around the left ankle.

Other names: brain gym exercises

conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

Other

Bimanual coordination,Hand-arm coordination ,Drinking & Strength training

Primary outcomes

  1. cognition

    Time frame: baseline assessment and after 12 sessions of educational kinesiology program training and conventional upper extremity coordination exercise training 3 sessions per week for 4 weaks

    the rate of improvement in cognition assessed by Rehacom system V 6.10.2.0 software.

Secondary outcomes

  1. manual dexterity and bimanual coordination

    Time frame: baseline assessment and after 12 sessions of educational kinesiology training and conventional upper extremities coordination exercises training 3 sessions per week for 4 weaks

    manual dexterity and bimanual coordination were assessed by purdue pegboard test model 32107 for purdue pegboard model 32020. assessed the rate of improvement in manual dexterity and bimanual coordination.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Effect of Educational Kinesiology Program on Cognition, Manual Dexterity and Bimanual Coordination in Patients With Multiple Sclerosis

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 3, 2025
Registry last updated
Jun 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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