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OpenTrials
Completed

NCT Number: NCT01886326

Eating Peanuts for Health

Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008). However, peanuts are a high fat, energy dense food and concerns about weight gain are widespread. Although research indicates that other characteristics of peanuts offset these properties, and that peanuts may be incorporated into diets without posing a threat to weight gain (Mattes et al., 2008), concern remains among policymakers, healthcare providers, and consumers. Furthermore, worry exists that eating salted peanuts may elevate blood pressure and that eating honey-roasted peanuts make elevate blood sugar. These fears create substantial obstacles to increased peanut consumption.

Recommendations to increase peanut consumption may be made, but if they are not followed, there will be no impact on health. Additional knowledge is needed on: (1) the acceptability of peanuts consumed on a chronic basis, (2) the chronic intake of moderate levels of peanuts and body weight, and 3) the effects of peanuts on blood pressure and blood sugar. The proposed research will examine the acceptability of long-term inclusion of a single form versus varied forms of peanuts in the diet. It is expected that responses will be varied among individuals with different personality characteristics (e.g., prefer sweet versus savory foods, hedonic versus non-hedonic eaters). A better understanding of how different segments of the population choose to include peanuts in their diet and how to optimize long-term consumption should provide insights for better marketing and improved health. Furthermore, it is anticipated that eating salty peanuts will not raise blood pressure and that eating honey-roasted peanuts will not raise blood sugar. Documenting this will add credibility to the evidence that peanuts do not cause weight gain, as well as reinforce recommendations to increase peanut consumption for their health benefits.

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Purdue University

West Lafayette, Indiana, 47907, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between 18 and 50 years of age
  • Weight stable (< 3 kg weight change within last 3 months)
  • Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
  • Constant habitual diet patterns within last 3 months
  • Willingness to eat all test foods (peanuts daily for 12 weeks)
  • No allergy to foods provided in the study (peanuts)
  • Not a daily peanut or tree nut consumer
  • Not planning to change use of medications known to influence appetite or metabolism
  • Not diabetic or hypertensive
  • No history of gastrointestinal pathology
  • Non-smoker for one year or more

Exclusion criteria

-

Treatment and study plan

Consumption of 42 grams of peanuts daily

Other

Consumption of the given 42 grams of peanuts daily without instructions for use (i.e. with/without meals, etc.)

Primary outcomes

  1. Change in Weight

    Time frame: 2, 4, 6, 8, 10, and 12 weeks

  2. Change in Blood Lipids

    Time frame: 4, 8, and 12 weeks

  3. Change in Blood Pressure

    Time frame: 2, 4, 6, 8, 10, and 12 weeks

  4. Change in Hedonics of peanut consumption

    Time frame: 12 weeks

    Participants will rate their liking of the sample each day using a visual analog scale.

  5. Change in Body Composition

    Time frame: 2, 4, 6, 8, 10, and 12 weeks

  6. Change in Fasting Blood Glucose

    Time frame: 4, 8, and 12 weeks

  7. Change in Cortisol

    Time frame: 4, 8, and 12 weeks

  8. Change in Insulin

    Time frame: 4, 8, and 12 weeks

  9. Change in Pulse

    Time frame: 2, 4, 6, 8, 10, and 12 weeks

Secondary outcomes

  1. Personality Questionnaires

    Time frame: At baseline visit

  2. Flavor attribute liking measures

    Time frame: At baseline

  3. Compliance

    Time frame: 12 weeks

    Participants will self-report compliance to study protocol using record sheets.

  4. Appetitive Ratings

    Time frame: 4, 8, and 12 weeks

    Collected on handheld computer

  5. Consumption Parameters

    Time frame: 12 weeks

    Participants will note if peanuts were eaten as a meal or snack, at what time, and with what other foods daily.

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Collaborators

  • United States Agency for International Development (USAID)

Registry information

Official study title

Peanut Consumption and Human Weight Management

Important dates

Study start
2010
Primary completion
2012
Study completion
2012
First posted
Jun 25, 2013
Registry last updated
Jun 25, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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