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OpenTrials
Completed

NCT Number: NCT04413825

Early Systolic Notching in Pulmonary Embolism

Venous thromboembolism (VTE), clinically seen as deep vein thrombosis (DVT) or pulmonary embolism (PE), is the third most common acute cardiovascular syndrome after myocardial infarction and stroke. In a study conducted by critical care and emergency physicians, lung ultrasonography (US) for pleural infarction areas, lower extremity venous US in terms of DVT, and focused cardiac US in terms of right ventricular strain were demonstrated with different diagnostic values for PE. However, no ultrasonographic method alone has a high diagnostic value for PE alone in the literature. In a recent study, it is stated that a new cardiac finding (early systolic notch- ESN) has high sensitivity (92%) and specificity (99%) in massive and submassive emboli. However, the limited patient population and the exclusion of many patient groups limits the applicability of the study and its use in other patient groups. With this study, it was aimed to determine the diagnostic value of ESN finding within the emergency department conditions by keeping the patient population wider.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Gazi University Facaulty of Medicine

Ankara, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing pulmonary CT angiography with suspicion of pulmonary embolism

Exclusion criteria

  • Pregnant women,
  • Patients under 18 years of age,
  • Those who received thrombolytic therapy,
  • Poor ultrasound imaging.

Treatment and study plan

Primary outcomes

  1. To determine the diagnostic accuracy of the ESN finding

    Time frame: 6 months

    What is the diagnostic value of ESN finding in patients with PE diagnosed with pulmonary CT angio?

Sponsors and collaborators

Lead sponsor

Gazi University

Other

Collaborators

  • Akdeniz University
  • Antalya Training and Research Hospital
  • Ege University
  • Izmir Katip Celebi University
  • Rize Üniversitesi

Registry information

Official study title

Diagnostic Accuracy of Early Systolic Notching in Pulmonary Embolism

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jun 4, 2020
Registry last updated
Feb 3, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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