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Completed

NCT Number: NCT06512948

Early Surgical Effects and Influencing Factors of High Tibial Osteotomy in the Treatment of Knee Osteoarthritis

Exploring the factors influencing postoperative functional recovery after high tibial osteotomy

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

The First Affiliated Hospital of Shandong First Medical University

Jinan, Shandong, 270000, China

About this study

A retrospective study was conducted on patients who underwent HTO at the First Affiliated Hospital of Shandong First Medical University from January 2018 to December 2020, and the preoperative and postoperative imaging indicators [medial proximal tibial angle (MPTA), joint line intersection angle (JLCA), hip-knee-ankle angle (HKA angle), knee weight-bearing line percentage (WBL%), postoperative distraction distance, postoperative distraction angle] and knee joint function score [including the American Hospital for Special Surgery (HSS) knee score, American Knee Society score (KSS), Lysholm score, Western Ontario and McMaster Universities Osteoarthritis Index score (WOMAC), and all were included in logistic regression analysis to study the surgical effect and impact of HTO factor

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medial knee OA, varus deformity is mainly in the tibia
  • Aged ≤70 years old, with higher requirements for future activities
  • Knee joint extension is limited to ≤10°, and flexion is >90°
  • Body Mass Index (BMI) ≤ 40
  • No subchondral bone wear

Exclusion criteria

  • There is a history of fracture or surgery of the lower limb on the operated side
  • Traumatic KOA
  • Combined with nerve, muscle or connective tissue diseases
  • Incomplete imaging data and loss of follow-up

Treatment and study plan

High tibial osteotomy

Procedure

Surgical treatment for patients with osteoarthritis and indications for high tibial osteotomy

Primary outcomes

  1. Imaging parameters

    Time frame: an average of 1 year after the surgery

    Medial proximal tibial angle

  2. Imaging parameters

    Time frame: an average of 1 year after the surgery

    Opening gap

  3. Imaging parameters

    Time frame: an average of 1 year after the surgery

    the weight bearing line ratio

  4. Imaging parameters

    Time frame: an average of 1 year after the surgery

    joint line convergence angle

  5. Imaging parameters

    Time frame: an average of 1 year after the surgery

    Hip-knee-ankle

  6. Imaging parameters

    Time frame: an average of 1 year after the surgery

    opening angle

Secondary outcomes

  1. function score

    Time frame: an average of 1 year after the surgery

    the US Hospital for special surgery knee-rating score

  2. function score

    Time frame: an average of 1 year after the surgery

    American knee society knee score

  3. function score

    Time frame: an average of 1 year after the surgery

    Lysholm

  4. function score

    Time frame: an average of 1 year after the surgery

    Western Ontario and McMaster Universities Osteoarthritis Index

Sponsors and collaborators

Lead sponsor

Shufeng Li

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 22, 2024
Registry last updated
Jul 22, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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