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OpenTrials
Completed

NCT Number: NCT05274685

Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome?

patients will be divided into two equal groups, each group including 50 adult patients with a confirmed diagnosis of covid, patients with acute kidney injury, the first group will be treated with early hemodialysis, second group will be conservative until there is an urgent need for dialysis

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Key information

Conditions

Multi Organ Failure Multiple Organ Failure Pathologic Processes Pathological Conditions, Signs and Symptoms Shock

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine, Sohag University

Sohag, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients (≥18 years old) with confirmed severe acute respiratory syndrome coronavirus 2 infections admitted to the ICU.

Exclusion criteria

  • •Malignancy.
  • Immuno-deficiency diseases.
  • Chronic diabetic, cardiac and hypertensive patients
  • autoimmune diseases.

Treatment and study plan

Haemodialysis

Procedure

continuous venovenous hemodiafiltration (CVVHDF) at a prescribed dose of 30-35 mL/kg/h of effluent and with regional citrate anticoagulation

Primary outcomes

  1. reduction of Sequential Organ Failure Assessment Score

    Time frame: 2 weeks

    prevention of multi-organ failure associated with covid including respiratorym circulatory, liver and renal failure

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Early Renal Replacement Therapy in COVID 19 Patients With AKI Improves the Prognosis of the Disease

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
Mar 10, 2022
Registry last updated
Mar 10, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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