Early Remote At-risk Diagnosis for Cerebral Palsy in Follow-up Clinics for High-risk Infants

Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age. This study will evaluate feasibility of a new screening procedure for early detection of CP in high-risk infants and investigate how such a procedure can be implemented in the Central Norwegian Regional Health Authority (CNRHA).

The most accurate method to detect and predict CP at an early age is the General Movement Assessment (GMA). GMA is based upon expert observations of infant spontaneous movements in a video. In Central-Norway such expertise is today only present at St. Olavs Hospital, Trondheim University Hospital. Video recordings by health personnel and parents will be used in follow-up programs within CNRHA for remote expert based GMA. In addition, machine learning models will be applied for automatic detection of CP.

Early identification of CP will lead to improved function and increased possibility to direct health care resources to the patients who need it most, independent of geographical and expert based constraints.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Cerebral Palsy Brain Damage, Chronic Brain Diseases Central Nervous System Diseases Disease Movement Disorders Nervous System Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

0 month–2 month

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Pediatrics, Nord-Trøndelag Hospital Trust, Levanger, Norway

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

hospitalized at a Neonatal Intensive Care Unit (NICU) within the Central Norway Regional Health Authority that is referred to follow-up in the Specialist Health Services containing a team of minimum a pediatrician and a physiotherapist.
at high-risk for adverse neurological outcomes as considered by the pediatrician on the basis of clinical judgement (example: serious asphyxia, prematurity, stroke, brain hemorrhage)

Exclusion criteria

Peripheral neuromotor disease e.g. brachial plexus injury
iatrogenic restricted movements (e.g. cast for clubfoot)

Treatment and study plan

Primary outcomes

Scorable video for remote GMA

Time frame: 1 week
Correlation of computer software data between standard video set-up and handheld smartphone video.

Time frame: 1 week
Predictability of GMA and computer-based assessment for development of CP

Time frame: 2 years
Predictability of GMA and computer-based assessment for development of CP

Time frame: 5 years

Sponsors and collaborators

Lead sponsor

St. Olavs Hospital

Other

Collaborators

Alesund Hospital
Helse Nord-Trøndelag HF

Registry information

Official study title

Feasibility of Remote Early At-risk Diagnosis for Cerebral Palsy in High-risk Infant Follow-up Clinics in The Central Norway Regional Health Authority

Acronym: In-Motion

Important dates

Study start: 2020
Primary completion: 2027
Study completion: 2027
First posted: Feb 27, 2020
Registry last updated: Jul 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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