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Completed

NCT Number: NCT06540092

Early Pregnancy Ultrasound Measurements and Prediction of First Trimester Pregnancy Loss.

Ultrasound measurements of fetus during first trimester may be an indicator of first trimester pregnancy loss. Investigators took 4 measurements of the fetus on 2 intervals during first trimester to confirm this hypothesis.

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Key information

Conditions

First Trimester Abortion

Age range

18 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

kasr Al Aini, Faculty of Medicine, Cairo University

Cairo, Old Cairo, 11562, Egypt

About this study

Ultrasound examination of gestational sac (GS) diameter, yolk sac (YS) diameter, crown rump length (CRL) diameter, embryonal heart rate (HR) using Samsung Medison SonoAce R3 through transvaginal probes (6.5 MHz) was conducted on 126 pregnant women. At least 2 scans were done for each participant one between 6-8 weeks and another one by the end of first trimester. Results then were compared to get the cut off values that can predict pregnancy loss.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • Healthy pregnant female patient in the reproductive age group; 18 - 40 years old.
  • Gestational age: 6 - 13 weeks of gestations.
  • Singlton or multifetal pregnancy.
  • Any mode of conception included spontaneous, after superovulation with clomiphene citrate or letrozole with, or without, intrauterine insemination (IUI), and in vitro fertilization (IVF) after superovulation with gonadotropins.

Exclusion criteria

  • • Patient with unsure date for the last menstrual period.
  • Pregnant women above 13 weeks gestation.
  • Patient with symptoms of threatened abortion or ectopic pregnancy at the initial antenatal visit.
  • Patient unable to come for follow up.
  • Any medical disorders as DM, HTN, …

Treatment and study plan

Ultrasound

Diagnostic Test

ultrasound measurements during first trimester

Primary outcomes

  1. The relation between early pregnancy ultrasound measurements (GSD, YSD, CRL, HR), viability, and continuation of pregnancy till 13 weeks of gestation.

    Time frame: 6-7 weeks

    2 measures of the fetus were obtained and compared to get first trimester pregnancy outcome

Sponsors and collaborators

Lead sponsor

Kasr El Aini Hospital

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Aug 6, 2024
Registry last updated
Aug 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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