Early Prediction and Diagnosis of Acute Kidney Injury

The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke. the main questions it aims to answer are :

* Early detection of acute kidney injury in patient with hemorrhagic stroke . * Decrease morbidity and mortality rate in patients with hemorrhagic stroke .

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Key information

Conditions

Early Diagnosis of Acute Kidney Injury

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Aswan university hospitals- Neurology Department

Aswān, 1240801, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients with hemorrhagic stroke presented to Aswan university hospital that will be fulfilled the following characters:

Age >18 years.
Both sex.
Cases of spontaneous onset

Exclusion criteria

Age < 18
Patients with traumatic hemorrhagic stroke.
Patients with brain tumors.
Patients with congenital anomalies of cerebral vessels e.g. AVM (arteriovenous malformation) and cerebral aneurysm.
Patients with history of any renal diseases

Treatment and study plan

Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.

Device

-Renal Resistive Index Measurement Method: Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer. First, the kidney is localised in the flanks with conventional B-mode ultrasonography, after which, color doppler images are acquired. The interlobar arteries were visualised, with the wavelength obtained by creating a 90-degree right-angle with the interlobar artery using a power doppler. After the manual determination of the peak systolic and end-diastolic velocities * RRI will be calculated by the device using the formula: RRI = (peak systolic velocity - end-diastolic velocity) / (peak systolic velocity). RRI will be measured three times for each kidney and averaged

Primary outcomes

Early detection of acute kidney injury in patient with hemorrhagic stroke

Time frame: within 2 days and 1 week

Sponsors and collaborators

Lead sponsor

Aswan University

Other

Registry information

Official study title

Renal Resistive Index as a Predictor of Acute Kidney Injury in Patient With Hemorrhagic Stroke

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2026
First posted: Sep 18, 2025
Registry last updated: Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.