Early-onset Rectal Cancer

The present study aimed to review the characteristics and outcome of early-onset rectal cancer in a subset of Egyptian patients aged 40 years or less. Since the previous studies assessed this point of research in CRC overall, the investigators opted to focus upon rectal cancer alone since it may represent a separate category, distinct from colon cancer, in this age group with regards to presentation, tumor behavior, and outcome.

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Key information

Conditions

Rectal Cancer Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases Rectal Neoplasms

Age range

10 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Mansoura university hospital

Al Mansurah, Dakahlia Governorate, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients of either gender aged 40 years or less who presented with rectal cancer of any stage were included to the study

Exclusion criteria

patients with colon cancer or other gastrointestinal cancer and patients who were lost to follow-up.

Treatment and study plan

Total mesorectal excision

Procedure

Radical resection of rectal cancer and draining lymph nodes

Primary outcomes

Local recurrence

Time frame: 36 months after surgery

recurrence of rectal cancer within the anatomic vicinity of the pelvis

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Patients With Early-Onset Rectal Cancer Aged 40 Year or Less Have Similar Oncologic Outcomes to Older Patients Despite Presenting in More Advanced Stage; A Retrospective Cohort Study

Important dates

Study start: 2008
Primary completion: 2017
Study completion: 2020
First posted: Aug 3, 2020
Registry last updated: Aug 3, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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