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NCT Number: NCT07559825

Early-Onset Colorectal Cancer Patients Too Young for Screening

This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.

Recruiting

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Key information

Conditions

Colorectal Cancer Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

35 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

Specifically, investigator want to investigate the effect of having a diagnosis of CRC before the age of 35 years on:disease stage at presentation, insurance status at diagnosis, treatment patterns by stage, and adjusted cancer-specific survival. The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Colorectal cancer

Exclusion criteria

  • No Colorectal cancer

Treatment and study plan

Colorectal cancer

Other

CRC is a disease that is often associated with older adults (<50 years). CRC remains the second most common cause of cancer death in males and the third most common cancer death in women. Despite this, CRC incidence has steadily declined in older adults; however, there is a concerning rise of incidence of colorectal cancer in young patients. The incidence of CRC in men and women under the age of 50 steadily increased 2.1 percent per year from 1992 through 2012.

Primary outcomes

  1. Age

    Time frame: 20 years

    colorectal cancer (CRC) patients younger than 35 years and comparing them against CRC patients older than 35 years of age.

Study contacts

Contact information is provided by the study sponsor or research team.

Crystee Cooper, DHEd

CONTACT

[email protected]

214-947-1280

Kavya Mankulangara

CONTACT

[email protected]

214-947-4604

Sponsors and collaborators

Lead sponsor

Methodist Health System

Other

Registry information

Official study title

Early-Onset Colorectal Cancer Patients Too Young for Screening: Outcomes and Treatment Patterns

Important dates

Study start
2020
Primary completion
2027
Study completion
2028
First posted
Apr 30, 2026
Registry last updated
Apr 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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