Early Incidence of Occupational Asthma Among Bakers, Pastry-makers and Hairdressers

Background: Occupational exposures are thought to be responsible for 10-15% of new-onset asthma cases in adults, with disparities across sectors. Because most of the data are derived from registries and cross-sectional studies, little is known about incidence of occupational asthma (OA) during the first years after inception of exposure. This study focuses on this early asthma onset period among young workers in the bakery, pastry making and hairdressing sectors in order to assess early incidence of OA in these "at risk" occupations according to exposure duration, and to identify risk factors of OA.

Methods: This study is a longitudinal retrospective study with a nested case-control to identify risk factors of OA. The assessment of incidence evolution is made by exploring a series of promotions (or retrospective cohorts) with increasing duration since at work. The study population is composed of subjects who graduated between 2001 and 2006 in sectors where they experience exposure to organic or inorganic allergenic or irritant compounds (with an objective of 150 subjects by year) and 250 young workers with no specific occupational exposure.

This study is a descriptive, monocentric, longitudinal and retrospective study with cross-sectional measurements.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Occupational Asthma Asthma Asthma, Occupational Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Occupational Diseases Respiratory Hypersensitivity Respiratory Tract Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Nancy

Nancy, 54000, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for the exposed group: to be graduated between 2001 and 2006 from nine vocational schools in Lorraine, North-Eastern France
for the "non-exposed" group: to be graduated in 2001 in the sale or the food sectors (butcher, pork butcher, caterer, cook job,…) from the same vocational schools

Exclusion criteria

asthma diagnosed before apprenticeship
for the "non-exposed" group: to have worked previously or later in a sector at risk with OA

Treatment and study plan

Primary outcomes

The early incidence of OA among young workers according to their sector of activity and exposure duration.

Time frame: 3-6 months after tle last inclusion

Secondary outcomes

The identification of risk factors of OA.

Time frame: 3-6 months after the last inclusion

Sponsors and collaborators

Lead sponsor

Central Hospital, Nancy, France

Other

Collaborators

Institut National de la Santé Et de la Recherche Médicale, France
University of Nancy

Registry information

Official study title

Evolution of the Incidence of Occupational Asthma at the Beginning of the Activity of Young Bakers, Pastry-makers and Hairdressers, and Exploration of Its Risk Factors

Acronym: ABCD

Important dates

Study start: 2008
Primary completion: 2010
Study completion: 2010
First posted: Mar 31, 2010
Registry last updated: Jul 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed