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Completed

NCT Number: NCT03798041

Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision

Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.

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Key information

Conditions

Surgical Wound Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710061, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • the patient with major abdominal incision.

Exclusion criteria

  • Pregnant woman
  • Patient with diabetes
  • Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
  • Severe lung diseases such as COPD and asthma
  • Patients undergoing emergent surgery or infectious surgery
  • Patients with surgical site infection or abdominal abscess
  • No autonomy, inability or unwillingness to participate in follow-up

Treatment and study plan

Debridement Within 24 Hours After Surgery

Behavioral

Debrided within 24 hours after surgery

Primary outcomes

  1. healing time, d (day)

    Time frame: From date of surgery to the date of stitches off (up to 1 month)

    since the ending of surgery to stitches off.

Secondary outcomes

  1. incidence of incision complications

    Time frame: From the date of surgery to stitches off (up to 1 month)

    The incision complications include infection, dehiscence, fat liquefaction, etc.

Sponsors and collaborators

Lead sponsor

First Affiliated Hospital Xi'an Jiaotong University

Other

Registry information

Official study title

Early Debridement Within 24 Hours After Surgery Compared Routine Debridement (24 Hours Later) for Wound Healing of Abdominal Incision

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Jan 9, 2019
Registry last updated
Dec 9, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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