Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT07602439

Early CMR in Acute MI

The goal of this observational study is to evaluate the clinical utility of cardiac magnetic resonance (CMR) in patients with acute myocardial infarction (AMI). This is a retrospective and prospective cohort study that has already enrolled a number of patients and will continue to enroll additional patients on a rolling basis.

The main question it aims to answer is:

How does CMR, performed acute phase, contribute to risk stratification, prognostic assessment, and long-term clinical management in patients with AMI?

Participants who have had an AMI will undergo CMR within one week of symptom onset. After discharge, they will be regularly followed up at 1, 3, 6, 9, and 12 months, and then every 6 months thereafter. Clinical outcomes will be collected during each follow-up visit.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Acute Myocardial Infarction (AMI)

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, 221000, China

About this study

This is an ambispective observational cohort study. The study will include patients who have already undergone CMR examination and meet the eligibility criteria, as well as consecutively enrolled patients who will undergo CMR during the prospective study period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 years or older.
  • Patients diagnosed with acute myocardial infarction.
  • Patients who complete cardiovascular magnetic resonance imaging during the acute phase after symptom onset.
  • Patients with available clinical, CMR, and follow-up data.

Exclusion criteria

  • History of previous myocardial infarction.
  • Severe renal insufficiency, defined as estimated glomerular filtration rate <30 mL/min/1.73 m².
  • Presence of malignant tumors.
  • Poor CMR image quality unsuitable for analysis.

Treatment and study plan

Cardiac Magnetic Resonance Imaging

Other

Cardiovascular magnetic resonance imaging will be used to assess cardiac structure, function, myocardial injury, infarct size, late gadolinium enhancement, microvascular obstruction, and other CMR-derived parameters. This is an observational cohort study, and no diagnostic test or treatment will be assigned by the investigators. CMR examinations have been or will be performed as part of routine clinical evaluation according to clinical indications.

Primary outcomes

  1. Major Adverse Cardiovascular Events (MACE)

    Time frame: through study completion, an average of 5 years

    A composite of cardiovascular death, non-fatal myocardial infarction, unplanned coronary revascularization, and hospitalization for heart failure. Assessed from the date of index hospitalization through the end of follow-up.

Secondary outcomes

  1. Cardiac Magnetic Resonance (CMR) Imaging Parameters

    Time frame: Baseline

    Presence of microvascular obstruction assessed by late gadolinium enhancement cardiovascular magnetic resonance imaging.

Sponsors and collaborators

Lead sponsor

The Affiliated Hospital of Xuzhou Medical University

Other

Registry information

Official study title

Exploring the Application and Value of Cardiac Magnetic Resonance in Acute Myocardial Infarction

Acronym: Early AMI-CMR

Important dates

Study start
2018
Primary completion
2046
Study completion
2046
First posted
May 22, 2026
Registry last updated
May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.