Stanley Dudrick's Memorial Hospital
Skawina, 32-050, Poland
NCT Number: NCT02997267
The aim of the study was to compare the restoration of the GI tract by the closure of protective ileostomy after low anterior resection for rectal cancer after 14 days and more than 3 months.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Skawina, 32-050, Poland
The closure of the protective ileostomy created during the low anterior resection for rectal cancer to protect the colo-rectal anastomosis is inevitable to restore the continuity of the gastrointestinal tract. It usually takes place several months after the primary surgery, because the patients starts chemotherapy and cannot undergo the procedure during the therapy. It results in the relative low quality of life of the patient, as well as often leads to complications. Therefore, it seem reasonable to close the stoma as soon as possible to take the burden off patient.
It is well known that the healing process of the anastomosis runs in the three phases, but only two first are crucial for the clinical result. The second takes place between 5th and 14th postoperative day. Therefore it should be possible to perform successful restoration of the GI tract already after two weeks after operation, and not after many moths.
The aim of the study was to compare the restoration of the GI tract after 14 days and more than 3 months, so to compare the traditional and early strategy.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Surgical closure of the protective ileostomy (reconnection of intestinal loops)
Time frame: 3 months after surgery
number of patients with the fistula of the anastomosis
Time frame: 3 months after surgery
Time to the beginning of adiuvant chemotherapy
Stanley Dudrick's Memorial Hospital
Other
The Early Closure of the Protective Ileostomy After Low Anterior Resection Enables Correct Start of Chemotherapy
Acronym: ECPIS
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