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Completed

NCT Number: NCT07625813

Early Bone Loss in Dental Implants

This retrospective observational study aims to evaluate early marginal bone loss around dental implants using panoramic radiographs. Radiographic records of patients who underwent mandibular dental implant surgery and implant-supported prosthetic rehabilitation will be reviewed. Marginal bone loss will be measured on the mesial and distal aspects of each implant at final restoration delivery and at follow-up periods after prosthetic loading. The study will also assess patient-, implant-, and prosthesis-related factors associated with marginal bone loss.

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Key information

Conditions

Dental Implant Bone Diseases Bone Diseases, Metabolic Marginal Bone Loss Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Dentistry, Bolu Abant İzzet Baysal University, Department of Periodontics

Bolu, Central, 14100, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals older than 18 years
  • Patients with mandibular dental implants
  • Availability of panoramic radiographs obtained after implant surgery and after prosthetic loading
  • Panoramic radiographs suitable for radiographic evaluation
  • Visibility of the mandibular inferior cortex and mental foramen on panoramic radiographs
  • Systemically healthy individuals

Exclusion criteria

  • Low-quality panoramic radiographs
  • Missing follow-up radiographs
  • Presence of systemic diseases or conditions that may affect bone metabolism

Treatment and study plan

Primary outcomes

  1. Change in Marginal Bone Loss Over Time

    Time frame: At final restoration delivery, 6 months, 18 months, and 60 months after prosthetic loading

    Marginal bone loss will be assessed on panoramic radiographs by measuring the linear distance from the implant platform to the nearest supporting crestal bone on the mesial and distal aspects of each implant. Mesial, distal, and mean marginal bone loss values will be recorded in millimeters.

Secondary outcomes

  1. Effect of implant length on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading

    The effect of implant length on mean marginal bone loss will be evaluated using regression analysis. Implant length will be recorded in millimeters from patient records and implant system information. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  2. Effect of implant diameter on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading.

    The effect of implant diameter on mean marginal bone loss will be evaluated using regression analysis. Implant diameter will be recorded in millimeters from patient records and implant system information. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  3. Effect of abutment height on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading.

    The effect of abutment height on mean marginal bone loss will be evaluated using regression analysis. Abutment height will be recorded in millimeters from prosthetic records. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  4. Effect of implant-tooth distance on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading.

    The effect of implant-tooth distance on mean marginal bone loss will be evaluated using regression analysis. Implant-tooth distance will be measured on panoramic radiographs as the horizontal distance between the implant and the adjacent natural tooth when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  5. Effect of implant-implant distance on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading.

    The effect of implant-implant distance on mean marginal bone loss will be evaluated using regression analysis. Implant-implant distance will be measured on panoramic radiographs as the horizontal distance between adjacent implants when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  6. Effect of emergence profile angle on mean marginal bone loss

    Time frame: Up to 60 months after prosthetic loading.

    The effect of emergence profile angle on mean marginal bone loss will be evaluated using regression analysis. Emergence profile angle will be recorded in degrees when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  7. Mean marginal bone loss according to implant placement level

    Time frame: Up to 60 months after prosthetic loading.

    Mean marginal bone loss will be compared according to implant placement level. Implant placement level will be categorized as crestal, subcrestal, or supracrestal according to the vertical position of the implant platform relative to the crestal bone level. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  8. Mean marginal bone loss according to prosthetic restoration type

    Time frame: Up to 60 months after prosthetic loading.

    Mean marginal bone loss will be compared according to prosthetic restoration type. Prosthetic restoration type will be categorized according to the type of implant-supported prosthetic rehabilitation, including single crown, fixed partial prosthesis, splinted crowns, full-arch fixed restoration, or removable prosthesis. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

  9. Mean marginal bone loss according to opposing arch condition

    Time frame: Up to 60 months after prosthetic loading.

    Mean marginal bone loss will be compared according to opposing arch condition. Opposing arch condition will be categorized according to the dentition or prosthetic status of the opposing arch. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

Sponsors and collaborators

Lead sponsor

Abant Izzet Baysal University

Other

Registry information

Official study title

Retrospective Evaluation of Early Bone Loss in Dental Implants

Acronym: Early Bone Los

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 4, 2026
Registry last updated
Jun 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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