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OpenTrials
Completed

NCT Number: NCT02518880

Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume

To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.

The main objective of this experiment is to determine the effects of parabolic flight on intravascular volume, and how these changes modulate the complex haemodynamics induced by the parabolas.

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Key information

Conditions

Healthy Volunteers

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Umr Ucbn/Inserm U1075 Comete

Caen, Basse-Normandie, 14032, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy volunteers (men or women),
  • aged from 18 to 55,
  • affiliated to a Social Security system,
  • who accept to take part in the study,
  • who have given their written stated consent,
  • who already participated in parabolic flights (even in the same campaign)
  • All subjects will pass a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection

Exclusion criteria

  • person who took part in a previous biomedical research protocol, of which exclusion period is not terminated,
  • pregnant women

Treatment and study plan

Parabolic flight

Other

plasma volume measurements

Other

Primary outcomes

  1. haemoglobin concentration

    Time frame: baseline

Sponsors and collaborators

Lead sponsor

University Hospital, Caen

Other

Registry information

Acronym: DYMCO

Important dates

Study start
2010
Primary completion
2012
First posted
Aug 10, 2015
Registry last updated
Aug 10, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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