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OpenTrials
Enrolling by Invitation

NCT Number: NCT07400510

DVT Evaluation Using POCUS for Diagnosis and Treatment

This study will include approximately 50 patients who will be enrolled if there is suspicion of lower extremity deep vein thrombosis (DVT). Each patient will receive a point-of-care ultrasound performed by physicians in an outpatient clinic. All patients will receive a subsequent confirmatory gold standard venous duplex ultrasonography. The investigators will compare time to diagnosis and treatment initiation and evaluate short-term clinical outcomes, including pulmonary embolism, hospitalization, ICU care, and mortality.

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Key information

Conditions

Deep Venous Thromboses Cardiovascular Diseases Embolism and Thrombosis Thrombosis Vascular Diseases Venous Thrombosis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Penn State Health, Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Penn State health patient
  • 18 years and older
  • English speaking
  • Presentation at clinical office with symptoms of a DVT

Exclusion criteria

  • Pregnancy
  • Less than 18 years old
  • Non-English speaking
  • Chronic Deep Vein Thrombosis

Treatment and study plan

STAT Venous Duplex

Diagnostic Test

STAT Venous Duplex

Routine Venous Duplex

Diagnostic Test

Routine Venous Duplex

Primary outcomes

  1. Number of Subjects Who Have Identical POCUS Result to Venous Duplex Result

    Time frame: 1 week

    Number of subjects whose ultrasound results using POCUS and subsequent confirmatory gold standard venous duplex ultrasound are identical, whether positive or negative for DVT.

Secondary outcomes

  1. Rate of Pulmonary Embolism

    Time frame: 3 months

    Rate of morbidity will be monitored for 3 months following the diagnosis of DVT by confirmatory venous duplex. Rate of morbidity will be identified through emergency room visits related to the DVT and hospitalizations related to the DVT.

  2. Rate of Stroke

    Time frame: 3 months

    Rate of morbidity will be monitored for 3 months following the diagnosis of DVT by confirmatory venous duplex. Rate of morbidity will be identified through emergency room visits related to the DVT and hospitalizations related to the DVT.

  3. Rate of Myocardial Infarction

    Time frame: 3 months

    Rate of morbidity will be monitored for 3 months following the diagnosis of DVT by confirmatory venous duplex. Rate of morbidity will be identified through emergency room visits related to the DVT and hospitalizations related to the DVT.

  4. Number of Subjects who Died

    Time frame: 3 months

    Number of subjects who died will be monitored for 3 months following the diagnosis of DVT by confirmatory venous duplex.

Sponsors and collaborators

Lead sponsor

Milton S. Hershey Medical Center

Other

Registry information

Official study title

Improving Lower Extremity DVT Outcomes in the Outpatient Setting: An Evaluation of 3-Point of Care Ultrasound for Timely Diagnosis and Treatment

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Feb 10, 2026
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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