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Completed

NCT Number: NCT00228514

Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub Study

At one site, patients participating in the Corona main study are asked to participate in the PET-substudy. Before and 6 months after study medication is started a Positron Emission Tomography (PET-scan) is performed to study the effect of rosuvastatin in Chronic Heart Failure on myocardial perfusion (reserve)

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Key information

Conditions

Rosuvastatin Cardiovascular Diseases Heart Diseases Heart Failure Positron Emission Tomography (PET)

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Research Site

Groningen, Netherlands

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients fulfilling the in and exclusion criteria of the CORONA study and separate informed consent for participation in the sub study.

Exclusion criteria

  • See above

Treatment and study plan

Rosuvastatin

Drug

Other names: Crestor

Positron Emission Tomography

Procedure

Primary outcomes

  1. To study the effect of rosuvastatin in Chronic Heart Failure on myocardial perfusion (reserve). Before and 6 months after study medication is started a Positron Emission Tomography (PET-scan) is performed.

Secondary outcomes

  1. To study the effect of rosuvastatin in Chronic Heart Failure on mismatch. Before and 6 months after study medication is started a Positron Emission Tomography (PET-scan) is performed.

Sponsors and collaborators

Lead sponsor

AstraZeneca

Industry

Registry information

Official study title

Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA) PET Sub Study

Important dates

Study start
2004
Study completion
2007
First posted
Sep 29, 2005
Registry last updated
Nov 15, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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