Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07288281

"Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant"

The goal of this prospective observational study is to report the duration of preoperative clear fluids fasting in patients undergoing liver transplant. It will also learn about the relationship between the duration of preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile at various anesthesia and transplant phases. The main questions it aims to answer are:

* How long liver recipient fast from clear fluids before liver transplant? * Is there any relationship between the duration of preoperative clear fluids fasting and changes in blood pressure and hear rate after the induction of anesthesia? * Is there any relationship between the duration of preoperative clear fluids fasting and blood glucose concentration, blood lactate concentration and acid base balance during anesthesia for liver transplant?

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Preoperative Clear Fluid Fasting Liver Transplant Recipient

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Clinical Centre of Medical University of Warsaw

Warsaw, Warszawa, 02-097, Poland

Location status: Recruiting

Location contact

Paula Dudek, medical doctor

CONTACT

[email protected]

+48225992001

About this study

Clear fluids include water, certain juices without pulp (like apple or grape), clear sodas, tea or coffee without milk or cream, clear broth, sports drinks, gelatin, and popsicles without fruit pulp or yogurt.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients scheduled for elective liver transplant

Exclusion criteria

  • patients unable to give detailed answer on clear fluid fasting due to severe hepatic encephalopathy or cognitive impairment
  • lack of written informed consent

Treatment and study plan

Primary outcomes

  1. clear fluids fasting

    Time frame: before the induction of anesthesia

    duration of preoperative clear fluids fasting in patients undergoing liver transplant

Other outcomes

  1. preoperative clear fluids fasting and changes in hemodynamic variables and metabolic profile

    Time frame: after patient's coming to the operating room before induction of anesthesia till the end of the anhepatic phase of liver transplantation (just before the repercussion of liver graft)

    The correlation between the duration of preoperative clear fluid fasting and changes in heart rate, mean arterial pressure, blood glucose concentration, blood pH, blood lactate concentration and standard base excess after the induction of anesthesia till the end of the anhepatic phase of liver transplantation.

Study contacts

Contact information is provided by the study sponsor or research team.

Paula Dudek, Medical Doctor

CONTACT

[email protected]

+49225992001

Sponsors and collaborators

Lead sponsor

Medical University of Warsaw

Other

Registry information

Official study title

"Duration of Preoperative Clear Fluids Fasting in Patients Undergoing Liver Transplant. A Prospective Observational Study: the "Timbarc-1" a Pilot Study"

Acronym: Timbarc-1

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Dec 17, 2025
Registry last updated
Jan 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.