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Completed

NCT Number: NCT07522775

Durability of the Effects of Low-Intensity Cognitive Behavioural Therapy

This exploratory study investigates the relapse condition in Hong Kong adults after low-intensity cognitive behavioural therapy (LICBT) treatment for 18 to 48 months with a 6-month interval. Individuals who received LICBT treatment between 2017 and 2020 will be recruited to assess their current mental health status. It is hypothesised that the improvements in depression and anxiety scores will be maintained at 18-to-48-month follow-up.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

New Life Psychiatric Rehabilitation Association

Hong Kong

About this study

The most prevalent common mental disorders worldwide are depression and anxiety. A local morbidity study illustrated that the prevalence rate for any common mental disorders is 13.3% in Hong Kong. Due to the huge demand for mental health services in Hong Kong, the waiting time for a new referral is around 1 year. Psychotherapies are suggested as first-line treatment for mood disorders, and while the effectiveness of traditional cognitive behavioural therapy (CBT) is consistently replicated, it is comparatively expensive and time-consuming. As a result, the delivery of traditional CBT alone cannot handle the huge demands for mental health service usage. To tackle this challenge, low-intensity cognitive behavioural therapy (LICBT) was developed in the United Kingdom (UK) to help individuals with lower severity of common mental disorders.

Local effectiveness of LICBT was supported by a pilot study in a Hong Kong community centre. In accordance with the UK National Institute for Health and Care Excellence (NICE) guidelines, service users were offered a brief treatment comprising six to eight structured sessions, in which they were assessed to identify the presenting problems and taught psychological tools to cope with their distress. Large effect sizes were reported for clinical improvements in depression and anxiety and satisfactory outcomes were also achieved. Despite the strong support for the short-term benefits of LICBT, depression and anxiety disorders are prone to relapse. Therefore, it is of great interest to investigate the long-term effects of LICBT.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 18 years old or above,
  • Capable of understanding Cantonese,
  • Received at least 2 sessions of LICBT since September 2017.

Treatment and study plan

Low-intensity cognitive behavioural therapy

Behavioral

Low-intensity cognitive behavioural therapy (LICBT) is a briefer form of the traditional cognitive behavioural therapy developed to help individuals with a lower severity of common mental disorders. LICBT is conducted in the form of individual guided self-help and comprises six to eight structured sessions in which psychological tools such as behavioural activation, worrying time, problem solving, exposure and habituation, and exposure and response prevention are taught.

Primary outcomes

  1. Patient Health Questionnaire-9 (PHQ-9)

    Time frame: Follow-up at 18-48 months after treatment

    The Patient Health Questionnaire-9 is a 9-item self-report questionnaire used to assess the severity of depressive symptoms. Total scores on the PHQ-9 range from 0 to 27. Scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe, and severe depression, respectively.

  2. Generalized Anxiety Disorder-7 (GAD-7)

    Time frame: Follow-up at 18-48 months after treatment

    The Generalized Anxiety Disorder-7 is a 7-item self-report questionnaire used to assess the severity of anxiety symptoms. Total scores on the GAD-7 range from 0 to 21. Scores of 5, 10, and 15 represent mild, moderate, and severe anxiety, respectively.

Sponsors and collaborators

Lead sponsor

New Life Psychiatric Rehabilitation Association

Other

Collaborators

  • Chinese University of Hong Kong

Registry information

Official study title

Durability of the Therapeutic Effects of Low-Intensity Cognitive Behavioural Therapy for Common Mental Disorders: a Long Term Follow-up on Relapse

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Apr 13, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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