IRCCS Ospedale San Raffaele
Milan, 20132, Italy
NCT Number: NCT05724537
Degenerative mitral regurgitation (MR) due to prolapse of the posterior leaflet is the most common dysfunction of the mitral valve (MV) in the Western world and is nowadays treated with a variety of surgical techniques. Quadrangular resection combined with annular plication and annuloplasty, as originally described by Carpentier, has been the standard approach for many years, before sliding/folding plasty and artificial chordae gained larger popularity.However, very few studies have been published on thevery long-term results (up to 20 years) of quadrangular resection and annular plication, often reporting only freedom from reoperation rather than from recurrent MR. This study aims to evaluate the very long-term (20 years) clinical and echocardiographic results of this approach, which was used for many years at the beginning of our mitral repair program.
Looking for future studies?
Notify Me18 year and older
All sexes
Observational
Milan, 20132, Italy
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Mitral regurgitation is treated removing the redundant tissue of the posterior leaflet, which is then reconstructed by sutures and plicating the posterior annulus
Time frame: Up to 20 years
Michele De Bonis
Other
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04045340
Cardiac Output, Low, Cardiovascular Diseases
Milan, Italy
View Trial DetailsNCT04787757
Cardiovascular Diseases, Heart Diseases
Milan, MI, Italy
View Trial DetailsNCT07027670
Aortic Valve Disease, Cardiac Surgical Procedures
Oxford, Oxfordshire, United Kingdom
View Trial DetailsNCT05531253
Cardiac Disease, Cardiovascular Diseases
Oxford, Oxfordshire, United Kingdom
View Trial Details