Duke Lupus Registry

Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger women.

The Duke Lupus Registry will collect information and blood samples from patients with lupus (systemic lupus erythematosus or cutaneous lupus) seen in the Duke Rheumatology clinics. The goal of this Registry is to understand how lupus changes over time so that we can improve the treatment of patients with lupus.

Recruiting

Interested in participating?

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Key information

Conditions

Systemic Lupus Erythematosus Autoimmune Diseases Connective Tissue Diseases Cutaneous Lupus Immune System Diseases Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Duke University Medical Center

Durham, North Carolina, 27710, United States

Location status: Recruiting

Location contact

Lisa G. Criscione-Schreiber, MD

SUB_INVESTIGATOR

Martin Tochacek, PhD

CONTACT

Megan E. B. Clowse, MD, MPH

PRINCIPAL_INVESTIGATOR

About this study

The Duke Lupus Registry is a prospective cohort comprised of patients with lupus seen in the Duke Rheumatology clinic.

The Duke Lupus Registry has two main purposes:

Improved patient care. By following disease activity scores and medication usage, we expect to improve our care of the patients seen in clinic.
Future research on lupus outcomes. This may encompass a broad array of areas, including but not limited to cardiovascular health, pregnancy and fertility, infections, medication use, quality of life, and depression.

At each office visit, patients will complete a questionnaire, physicians will measure lupus activity, and patients may be asked to provide a small blood sample. Patients will not be required to make extra visits to Duke in order to participate -- all paperwork and blood draws will occur during a regularly scheduled office visit with the physician.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of Systemic Lupus Erythematosus or Cutaneous Lupus
Patient of a rheumatologist at Duke University Medical Center

Exclusion criteria

Inability to travel to Duke for follow-up visits
Inability to speak English
Not able to provide informed consent

Study contacts

Contact information is provided by the study sponsor or research team.

Laura Neil

CONTACT

[email protected]

(919) 684-8936

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Important dates

Study start: 2007
Primary completion: 2028
Study completion: 2028
First posted: Aug 8, 2007
Registry last updated: Jan 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting