Samsung Medical Center
Seoul, South Korea
NCT Number: NCT03486769
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in post stroke patients. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through three conditions of transcranial direct current stimulation with for 30 minutes. Three conditions are 1) Dual stimulation 1: i) anodal stimulation on ipsilesional primary motor cortex and cathodal stimulation on contralesional primary motor cortex, ii) anodal stimulation on ipsilesional premotor cortex and cathodal stimulation on contralesional supraorbital area. 2) Dual stimulation 2: i) anodal stimulation on ipsilesional primary motor cortex and cathodal stimulation on contralesional primary motor cortex, ii) anodal stimulation on ipsilesional anterior intraparietal sulcus and cathodal stimulation on contralesional supraorbital area. 3) Single stimulation: anodal stimulation on ipsilesional primary motor cortex and cathodal stimulation on contralesional primary motor cortex.
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Notify Me19 year–85 year
All sexes
Interventional
Not applicable
Seoul, South Korea
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
stimulating primary motor cortex with anodal transcranial direct current stimulation
Other names: primary motor cortex anodal stimulation
stimulating premotor cortex with anodal transcranial direct current stimulation
Other names: premotor cortex anodal stimulation
stimulating anterior intraparietal sulcus with anodal transcranial direct current stimulation
hand motor task for 30 minutes during transcranial direct current stimulation
Time frame: Baseline and after intervention (approximately 2 weeks)
measure the motor threshold and amplitude of motor evoked potential in first dorsal interosseous muscle.
Time frame: Baseline and after intervention (approximately 2 weeks)
Nine-Hole Peg Test is used to measure finger dexterity in patients with various neurological diagnoses.
Time frame: Baseline and after intervention (approximately 2 weeks)
measure the hand strength (grip and tip pinch)
Time frame: Baseline and after intervention (approximately 2 weeks)
box and block test measures unilateral gross manual dexterity
Time frame: Baseline and after intervention (approximately 2 weeks)
Neuroplasticity measure
Time frame: Baseline and after intervention (approximately 2 weeks)
Cortical activation is measured by functional Near-Infrared-Spectroscopy (fNIRS) (NIRScout, NIRx, Germany)
Samsung Medical Center
Other
Effect of Dual Site-dual Channel Non-invasive Brain Stimulation for Recovery of Motor Function in Stroke Patients
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