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Completed

NCT Number: NCT03486795

Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex, ii) anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 2) M1 stimulation: anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex; 3) PMC stimulation: anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 4) sham stimulation

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Key information

Conditions

Healthy

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Samsung Medical Center

Seoul, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects with age over 19 years old

Exclusion criteria

  • history of disorders involving central nervous system
  • patients with severe medial or psychiatric disease

Treatment and study plan

M1 stimulation

Device

stimulating primary motor cortex with anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex

PMC stimulation

Device

stimulating premotor cortex with anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area

Sham stimulation

Device

sham stimulation over both primary motor cortex and premotor cortex

Primary outcomes

  1. Changes in motor evoked potential

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measure the motor threshold and amplitude of motor evoked potential in first dorsal interosseous muscle

Secondary outcomes

  1. Changes in sequential motor task

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measures motor functional and dexterity of hand

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Registry information

Official study title

Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Motor Function in Healthy Subjects

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Apr 3, 2018
Registry last updated
Sep 20, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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