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Completed

NCT Number: NCT03486808

Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation

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Key information

Conditions

Healthy

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Samsung Medical Center

Seoul, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects with age over 19 years old

Exclusion criteria

  • history of disorders involving central nervous system
  • patients with severe medical or psychiatric disease

Treatment and study plan

IFG stimulation

Device

stimulating left inferior frontal cortex with transcranial direct current stimulation for 30 minutes

DLPFC stimulation

Device

stimulating left dorsolateral prefrontal cortex with transcranial direct current stimulation for 30 minutes

Sham stimulation

Device

sham stimulation over both left inferior frontal cortex and dorsolateral prefrontal cortex

Primary outcomes

  1. Korean Boston naming test

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measures naming ability thorough picture naming test

  2. Verbal 3 back test

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measure working memory

Secondary outcomes

  1. Korean Color Word Stroop test

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measures selective attention and executive function

  2. Controlled Oral Word Association Test

    Time frame: Baseline and after intervention (approximately 30 minutes)

    measure verbal fluency

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Registry information

Official study title

Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Language and Cognitive Function in Healthy Subjects

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Apr 3, 2018
Registry last updated
Sep 20, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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