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NCT Number: NCT06939387

Drug-induced Kidney Injury Model

To establish the prediction model of renal dysfunction in patients with drug-induced renal injury and study the prognosis of different drug treatments

Recruiting

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Key information

Conditions

Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, 311121, China

Location status: Recruiting

Location contact

Xiaolan Ye, Master

CONTACT

[email protected]

+86-0571-85893117

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Drug-induce acute kidney injury

Exclusion criteria

  • 1.Dialysis patients; 2.No baseline creatinine; 3.Obstructive AKI; 4.Clinical data were incomplete.

Treatment and study plan

Observational study, no intervention

Other

Observational study, no intervention

Primary outcomes

  1. Model performance metrics assessed by AUC-ROC, accuracy and F1-score using 10-fold cross-validation

    Time frame: through study completion, an average of 6 months

    The prognosis of renal function was evaluated by measuring creatinine and proteinuria by laboratory tests. Predict outcomes using machine learning methods. And the prediction effect of the prediction model was evaluated by AUC-ROC, F1, accuracy and other indicators.

Secondary outcomes

  1. The rate at which creatinine falls

    Time frame: 7 days, 1 month, 3 months after treatment

Study contacts

Contact information is provided by the study sponsor or research team.

Ping Huang, doctor

CONTACT

[email protected]

+86-0571-85893117

xiaolan Ye, master

CONTACT

[email protected]

+86-0571-85893117

Sponsors and collaborators

Lead sponsor

Zhejiang Provincial People's Hospital

Other

Collaborators

  • Aksu district first People's Hospital
  • Hangzhou Linping District first People's Hospital
  • Ningbo Yinzhou District Second Hospital
  • Taizhou Enze Medical Center Group
  • Wucheng District First People's Hospital

Registry information

Official study title

Establishment, Evaluation and Treatment Strategy of Drug-induced Kidney Injury Model

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Apr 22, 2025
Registry last updated
Apr 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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