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Completed

NCT Number: NCT05123521

Drug Abuse Among Elective Surgeries: an Observational Study.

Drug abusers and addicts form a challenge to the anesthetist because of the added potential risks involved in the administration of anesthesia to this subset of patients, including potential unforeseen drug-drug interactions. In this study, we aimed at screening all patients scheduled for elective orthopedic or general surgeries at the Cairo University Teaching Hospital during a set period of time for the most commonly abused drugs in Egypt.

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Key information

Conditions

Drug Abuse Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

15 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cairo University

Cairo, Giza Governorate, 1234, Egypt

About this study

All patients included in the study consented to take part in this study. Each patient was asked to answer a questionnaire and submit a urine sample in order to be screened for the most commonly abused drugs in Egypt (hashish, tramadol, benzodiazepine, and morphine). Patients were then followed up both intra and post-operatively. Values of patient vital signs, Richmond Agitation-Sedation Scale (RASS) scores as well as clinical recovery scores (CRS) were all diligently recorded and analyzed.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male or female patients classified as American Society of Anaesthesiology (ASA) I or II patients
  • patients between 15 and 60 years of age
  • patients scheduled for elective surgery.

Exclusion criteria

  • emergency surgery
  • those with disturbed conscious levels
  • history of psychological illness
  • who refused to give consent

Treatment and study plan

Urine analysis

Diagnostic Test

Urine was then tested for evidence of substance abuse using the multi-drug screen panel dip steak ABONtm (Abon Biopharm (Hangzhou) CO., Ltd) which is a lateral flow chromatographic immunoassay . It allowed for qualitative detection of multiple drugs in a single run. This kit was chosen for its ability to detect the most commonly abused substances in Egypt, namely: opioids, benzodiazepines, hashish, and tramadol. A single coloured line at region C for of a specific drug indicated a positive result, whilst two coloured lines at both regions C and T indicated a negative result. The absence of coloured lines was an indication of the invalidity of the particular kit, and the kit was discarded.

Primary outcomes

  1. urine analysis

    Time frame: THREE MONTHS

    multi-drug screen panel dip steak (Abon Biopharm (Hangzhou) , Ltd)

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Incidence of Drug Abuse at the Cairo University Teaching Hospital Among Patients Who Underwent Elective Surgeries

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Nov 17, 2021
Registry last updated
Nov 17, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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