Skip to main content
OpenTrials
Completed

NCT Number: NCT02325895

Dried Plums for Bone Health in Older Postmenopausal Women

The objective of the investigators current study was to examine whether 50 g dried plum would be as effective as 100 g dried plum in reversing bone loss in osteopenic older postmenopausal women.

Completed

Looking for future studies?

Notify Me

Key information

Age range

65 year–79 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Forty-five randomly assigned into one of three treatment groups: 1) 50g dried plum; 2) 100g dried plum; and 3) control (0g dried plum). All groups received 500mg calcium and 400 IU vitamin D as a daily supplement. Blood samples were collected at baseline, 3 and 6 months to assess biomarkers of bone turnover. Physical activity recall and 3-day food records were obtained at baseline, 3 and 6 months to examine physical activity and dietary confounders as potential covariates

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMD t-score of L1-L4 between -1 to -2.5 standard deviation of the mean
  • Age 65 to 79

Exclusion criteria

  • BMD t-score at any site fell below 2.5 standard deviation of the mean
  • Subjects treated with calcitonin, bisphosphonates, raloxifene and/or anabolic agents such as parathyroid hormone and growth hormone, or steroids within three months before the start of the study
  • Metabolic bone disease, renal disease, cancer, CVD, diabetes mellitus, respiratory disease, gastrointestinal disease, liver disease or other chronic diseases, heavy smoking (more than twenty cigarettes/day) and current use of any prescription medications known to alter bone and calcium metabolism
  • Regularly consumed dried plum or prune juice were not included in the study.

Treatment and study plan

Dried Plum

Other

Three doses of dried plum (0 g, 50 g and 100g) were used as intervention.

Primary outcomes

  1. Bone Mineral Density

    Time frame: 6 months

Secondary outcomes

  1. Changes from baseline in bone specific alkaline phosphatase at 3 months and 6 months

    Time frame: baseline, 3 months and 6 months

Sponsors and collaborators

Lead sponsor

San Diego State University

Other

Collaborators

  • Florida State University

Registry information

Official study title

Effect of Dried Plum on Bone and Bone Biomarkers in Older Women

Important dates

Study start
2012
Primary completion
2014
Study completion
2014
First posted
Dec 25, 2014
Registry last updated
Dec 25, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.