Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction

Dose titration of propofol for tracheal intubation in children with sevoflurane inhalation induction.

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Key information

Conditions

Pediatric Urinary Disorders

Age range

6 month–5 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pediatric patients scheduled for elective day case surgery were enrolled.

Exclusion criteria

History of obstructive sleep apnea
Evidence of cardiorespiratory disease
Those who were obese or allergic to any of the anesthetic agents in this study
Those with an anticipated difficult airway, full stomach
History of malignant hyperthermia or other myopathy were excluded.

Treatment and study plan

Propofol

Drug

intravenous propofol with sevoflurane inhalation induction

Primary outcomes

Assessment of intubation conditions

Time frame: 30 minutes after the surgery

Assessment of intubation conditions (vocal cord, intubation condition, cough, movement) , peri-induction HR and BP change, post-operative agitation socre at recovery room. ED50 and ED 95 of each group by uring Dixon's up and down methods.

peri -induction period -comparison of above factors among each groups (GroupA: ETSevo 3vol%, Group B: ETSevo 3.5vol%, Group: ET Sevo 4vol%)

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Important dates

Study start: 2009
Primary completion: 2010
Study completion: 2011
First posted: Mar 10, 2010
Registry last updated: Feb 19, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.