Dose Response Effect of Probiotics for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults

The purpose of this study is to determine the dose response effect of probiotic capsules for the prevention of antibiotic-associated diarrhea (AAD).

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Key information

Conditions

Antibiotic-associated Diarrhea Diarrhea Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

30 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Changhai Hospital

Shanghai, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age 30-70 years
initiating antibiotic therapy
informed consent

Exclusion criteria

current diarrhea
life threatening illness
habitual probiotic use

Treatment and study plan

Probiotic

Dietary Supplement

L. acidophilus, L. paracasei, B. lactis; 2.5 billion cfu capsule once per day

Placebo

Other

Placebo

Primary outcomes

Incidence of antibiotic-associated diarrhea

Time frame: 5 weeks after antibiotic discontinuation

Sponsors and collaborators

Lead sponsor

Changhai Hospital

Other

Registry information

Official study title

Dose Response Effect of a Proprietary Probiotic Formula for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults

Important dates

Study start: 2010
Primary completion: 2011
Study completion: 2011
First posted: Jun 14, 2010
Registry last updated: Sep 20, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed