Dose Finding Study With CYT003-QbG10 in Patients With House Dust Mite Allergy

The purpose of the study is to test whether vaccinations with CYT003-QbG10 can improve allergy symptoms in patients with house dust mite allergy. The active treatment will be compared against placebo.

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Key information

Conditions

Rhinoconjunctivitis Allergies Hypersensitivity Immune System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Cytos Investigator Sites, Paide, Tartu, Tallin, Rakvere, Estonia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Perennial allergic rhinoconjunctivitis due to clinically relevant allergy towards house dust mite allergens
Further criteria as defined in the study protocol

Exclusion criteria

Clinically manifested seasonal allergy/-ies which is/are expected to interfere with the patient's study treatment schedule and/or assessments
Clinically relevant perennial allergy/-ies other than house dust mites allergy
Contraindication to any study test or procedure
Further criteria as defined in the study protocol

Treatment and study plan

CYT003-QbG10

Drug

subcutaneous injection

Placebo

Drug

subcutaneous injection

Primary outcomes

Rhinoconjunctivitis symptom and medication scores

Time frame: Pre- / Post-Treatment

Sponsors and collaborators

Lead sponsor

Cytos Biotechnology AG

Industry

Registry information

Official study title

Double-blind, Placebo-controlled Dose-finding Study With CYT003-QbG10 in Adult Patients With Rhinoconjunctivitis Due to House Dust Mite Allergy

Important dates

Study start: 2008
Primary completion: 2010
Study completion: 2010
First posted: Dec 2, 2008
Registry last updated: Nov 15, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed