Skip to main content
OpenTrials
Completed

NCT Number: NCT01425554

Doppler Sonography, MR Venography, Plethysmography for the Diagnosis of CCSVI

This study is aimed at evaluation of diagnostic value of Doppler sonography, MR venography and air-plethysmography for the assessment of abnormalities in the internal jugular veins, with catheter venography as the reference test.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Chronic Cerebrospinal Venous Insufficiency

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Euromedic Specialis Clinics; ul. Rolna 18

Katowice, 40-555, Poland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

  • Patients group

Inclusion criteria

  • confirmed diagnosis of multiple sclerosis

Exclusion criteria

  • coexisting another neurologic pathology (e.g. stroke, Parkinson disease)
  • significant stenosis of carotid or vertebral arteries
  • other significant abnormalities of blood vessels of the upper part of the body
  • tricuspid valve incompetence
  • allergy to iodine contrast dye
  • chronic renal failure
  • pregnancy
  • other severe comorbidities or significant abnormalities in standard lab tests
  • Healthy volunteers.

Inclusion criteria

  • none

Exclusion criteria

  • confirmed diagnosis of multiple sclerosis or related pathologies (CIS, NMO)
  • coexisting another neurologic pathology (e.g. stroke, Parkinson disease)
  • significant stenosis of carotid or vertebral arteries
  • other significant abnormalities of blood vessels of the upper part of the body
  • tricuspid valve incompetence

Treatment and study plan

Doppler sonography of internal jugular veins

Other

Doppler sonography of internal jugular veins

Magnetic resonance venography of internal jugular veins

Other

Magnetic resonance venography of internal jugular veins

Air-plethysmography of the neck

Other

Air-plethysmography of the neck

Catheter venography of internal jugular veins

Other

Catheter venography of internal jugular veins

Primary outcomes

  1. Positive and negative predictive value of Doppler sonography, MR venography and air-plethysmography

    Time frame: All non-invasive test are done up to 14 days prior to catheter venography

    Positive and negative predictive value of Doppler sonography,MR venography and air-plethysmography for the detecting of vascular malformation in the internal jugular veins with catheter venography as the reference test

Sponsors and collaborators

Lead sponsor

Euromedic Specialist Clinics, Poland

Other

Registry information

Official study title

Doppler Sonography, Magnetic Resonance Venography, Air-plethysmography in the Non-invasive Diagnostics of Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Important dates

Study start
2011
Primary completion
2013
Study completion
2013
First posted
Aug 30, 2011
Registry last updated
Feb 10, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.