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OpenTrials
Completed

NCT Number: NCT04068363

Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant

Liver transplantation (LT) represents the gold-standard therapy for the treatment in case of dreadful liver pathologies . It is thus a main concern to optimize the results in terms of post-LT survivals. The effect of gender match on post-transplant outcome is still debatable. Hormonal , and size difference between female and male may be proposed to affect the post transplant outcome . The aim of this study is to evaluate the effect of donor-recipient gender mismatch on survival rates

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Key information

Conditions

Donor to Recipient Gender Mismatch in LDLT

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hanaa El Gendy

Cairo, Ain Shams University Specialized Hospital, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult Egyptian Patients >18 years.

Exclusion criteria

  • Patient refusal.
  • Patients who underwent re-transplantation before discharge from the ICU after the first liver transplant.
  • Intraoperative cardiac arrest or immediately postoperative cardiac arrest within the first 6 hours postoperative.
  • Massive blood loss.
  • Pre-existing renal failure requiring hemodialysis or continuous hemofiltration.
  • Pregnancy.

Treatment and study plan

Non Interventional

Other

non interventional study

Primary outcomes

  1. 2 years survival post liver transplant.

    Time frame: 3 months

    The primary outcome will be survival at 2 years post liver transplant

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant: A Single Centre Retrospective Study

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Aug 28, 2019
Registry last updated
Feb 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.