suturing meniscal augmented
Proceduremeniscal tear sutured + bone marrow injection/collagen membrane
Other names: meniscal wrapping
NCT Number: NCT03968029
This study will compare meniscal healing of non-vascularised area augmented or not by bone marrow injected under a protective collagen membrane (meniscal wrapping)
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Notify Me15 year–45 year
All sexes
Interventional
Not applicable
Centre Hospitalier Universitaire Vaudois - CHUV, Lausanne, Canton of Vaud, Switzerland
Historically, meniscus was considered as none essential for knee joint, and its removal by meniscectomy was the first-line treatment. Many studies have shown a negative progress towards osteoarthritis after meniscus ablation. This approach has gradually changed to preserve this meniscal capital, making way for new treatments as sutures. However the vascular organization of the meniscus is crucial for its cure. The healing potential of lesions in the meniscus non-vascularised aera is considered insufficient, and are often treated by a partial meniscectomy, resulting in a high risk of osteoarthritis. It appears therefore necessary to develop new strategies, as meniscal wrapping, to preserve meniscus presenting this type of damage.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
meniscal tear sutured + bone marrow injection/collagen membrane
Other names: meniscal wrapping
meniscal tear sutured
Time frame: 12 and 24 months after treatment
Arthrography (arthro-CT)
Time frame: baseline and 3, 12 and 24 months after treatment
Changes in the 5 subscales of KOOS as assessed from baseline to 24 months post-surgery
Time frame: baseline and 3, 12 and 24 months after treatment
Change in physical pain and function as assessed by IKDC score from baseline to 24 months post-surgery
Time frame: baseline and 3, 12 and 24 months after treatment
Change in functional health and well-being as assessed by SF-12 Survey from baseline to 24 months post-surgery
Time frame: up to 24 months
Number of readmission for meniscus tear
Time frame: 12 months after treatment
Imaging: MRI
Time frame: up to 24 months
Post-operative data collection: inflammation, pain, recurrent tear of the meniscus, instability or stiffness joint, perimeniscal cyst formation, hemarthrosis or effusion.
Centre Hospitalier Universitaire Vaudois
Other
Does Wrapping With Bone Marrow Injection Enhance Healing of Meniscal Sutures Into the Non-vascular Area: A Prospective Randomised Study
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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